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MedKoo Cat#: 596221 | Name: JHU-75528 C-11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JHU-75528 C-11 is a Radiotracer for PET Imaging of CB1 Cannabinoid Receptors.

Chemical Structure

JHU-75528 C-11
JHU-75528 C-11
CAS#942063-86-7

Theoretical Analysis

MedKoo Cat#: 596221

Name: JHU-75528 C-11

CAS#: 942063-86-7

Chemical Formula: C2211CH21Cl2N5O2

Exact Mass: 468.1187

Molecular Weight: 469.35

Elemental Analysis: C, 58.65; H, 4.51; Cl, 15.11; N, 14.92; O, 6.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
JHU-75528 C-11; 11c-Omar; JHU75528 C-11; JHU 75528 C-11;
IUPAC/Chemical Name
4-cyano-1-(2,4-dichlorophenyl)-5-(4-(methoxy-11C)phenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
InChi Key
MCNQUWLLXZZZAC-BJUDXGSMSA-N
InChi Code
InChI=1S/C23H21Cl2N5O2/c1-32-17-8-5-15(6-9-17)22-18(14-26)21(23(31)28-29-11-3-2-4-12-29)27-30(22)20-10-7-16(24)13-19(20)25/h5-10,13H,2-4,11-12H2,1H3,(H,28,31)/i1-1
SMILES Code
[11CH3]Oc1ccc(c2n(c3c(Cl)cc(Cl)cc3)nc(C(NN4CCCCC4)=O)c2C#N)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 469.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 29667807. 11: Yuan L, Li Z, Zhang X, Yuan X. Crystal Structure and Biological Activity of (3-Methyl-1,5-dioxaspiro[5.5]undecan-3-yl)Methanol Synthesized with Nanosolid Superacid. J Nanosci Nanotechnol. 2017 Apr;17(4):2624-627. PubMed PMID: 29664249. 12: Nguyen BD. C-11 Choline and F-18 Fluciclovine PET/CT demonstration of annular pancreas. Dig Liver Dis. 2018 Mar 20. pii: S1590-8658(18)30236-6. doi: 10.1016/j.dld.2018.03.018. [Epub ahead of print] PubMed PMID: 29631936. 13: González-Domínguez J, Expósito RR. ParBiBit: Parallel tool for binary biclustering on modern distributed-memory systems. PLoS One. 2018 Apr 2;13(4):e0194361. doi: 10.1371/journal.pone.0194361. eCollection 2018. PubMed PMID: 29608567; PubMed Central PMCID: PMC5880350. 14: Viney NJ, Yeang C, Yang X, Xia S, Witztum JL, Tsimikas S. Relationship between "LDL-C", estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide. 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