Synonym
Solven; Jamylene; DSS-danthron; Danthron - DSS;
IUPAC/Chemical Name
Butanedioic acid, sulfo-, 1,4-bis(2-ethylhexyl)ester, sodium salt, mixt. with 1,8-dihydroxy-9,10-anthracenedione
InChi Key
WVZAWUZJHCJUNU-UHFFFAOYSA-M
InChi Code
InChI=1S/C14H8O4.C12H22O7S.C8H18.Na/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16;1-3-5-6-9(4-2)8-19-12(15)10(7-11(13)14)20(16,17)18;1-4-6-7-8(3)5-2;/h1-6,15-16H;9-10H,3-8H2,1-2H3,(H,13,14)(H,16,17,18);8H,4-7H2,1-3H3;/q;;;+1/p-1
SMILES Code
O=C(OCC(CC)CCCC)C(S(=O)([O-])=O)CC(OCC(CC)CCCC)=O.O=C1C2=C(C=CC=C2O)C(C3=CC=CC(O)=C13)=O.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
686.78
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Muhammad Sarfraz R, Bashir S, Mahmood A, Ahsan H, Riaz H, Raza H, Rashid Z, Atif Raza S, Asad Abrar M, Abbas K, Yasmeen T. APPLICATION OF VARIOUS POLYMERS AND POLYMERS BASED TECHNIQUES USED TO IMPROVE SOLUBILITY OF POORLY WATER SOLUBLE DRUGS: A REVIEW. Acta Pol Pharm. 2017 Mar;74(2):347-356. Review. PubMed PMID: 29624239.
2: Zhang L, Wen Y, He T, Wang M, Xu P. [Determination of residual cyclohexanone in disposable infusion set by gas chromatography]. Zhongguo Yi Liao Qi Xie Za Zhi. 2014 Sep;38(5):381-2, 385. Chinese. PubMed PMID: 25597092.
3: Xu C, Ye Z, Li D, Zhou D, Shui W. [Study on technology in preparation of Fructus Auranti extract]. Zhongguo Zhong Yao Za Zhi. 2011 Nov;36(21):2971-4. Chinese. PubMed PMID: 22308686.
4: Horisawa E, Kubota K, Tuboi I, Sato K, Yamamoto H, Takeuchi H, Kawashima Y. Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium. Pharm Res. 2002 Feb;19(2):132-9. PubMed PMID: 11883639.
5: Frize M, Wang L, Ennett CM, Nickerson BG, Solven FG, Stevenson M. New advances and validation of knowledge management tools for critical care using classifier techniques. Proc AMIA Symp. 1998:553-7. PubMed PMID: 9929280; PubMed Central PMCID: PMC2232056.
6: Frize M, Solven FG, Stevenson M, Nickerson B, Buskard T, Taylor K. Computer-assisted decision support systems for patient management in an intensive care unit. Medinfo. 1995;8 Pt 2:1009-12. PubMed PMID: 8591352.
7: Dhingra S, Solven F, Wilson A, McCarthy DS. Hypomagnesemia and respiratory muscle power. Am Rev Respir Dis. 1984 Mar;129(3):497-8. PubMed PMID: 6703506.
8: Newton DW, Murray WJ, Lovell MW. pKa determination of benzhydrylpiperazine antihistamines in aqueous and aqueous methanol solutions. J Pharm Sci. 1982 Dec;71(12):1363-6. PubMed PMID: 6130141.
