MedKoo Cat#: 596097 | Name: ZM-39923

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZM39923 is a Janus kinase inhibitor with IC50 of 10 nM.

Chemical Structure

ZM-39923
ZM-39923
CAS#273727-89-2

Theoretical Analysis

MedKoo Cat#: 596097

Name: ZM-39923

CAS#: 273727-89-2

Chemical Formula: C23H25NO

Exact Mass: 331.1936

Molecular Weight: 331.45

Elemental Analysis: C, 83.34; H, 7.60; N, 4.23; O, 4.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ZM-39923; JAK3 inhibitor IV; ZM 39923; ZM39923;
IUPAC/Chemical Name
3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-one
InChi Key
JSASWRWALCMOQP-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H25NO/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22/h3-13,16,18H,14-15,17H2,1-2H3
SMILES Code
O=C(C1=CC=C2C=CC=CC2=C1)CCN(C(C)C)CC3=CC=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 331.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Vidro-Kotchan E, Yendluri BB, Le-Thai T, Tsin A. NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGFβ. Curr Eye Res. 2011 Apr;36(4):370-8. doi: 10.3109/02713683.2010.549601. Epub 2011 Feb 10. PubMed PMID: 21309688; PubMed Central PMCID: PMC4487514.