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MedKoo Cat#: 558019 | Name: K 259-2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

K 259-2 is a phosphodiesterase inhibitor.

Chemical Structure

K 259-2
K 259-2
CAS#102819-46-5

Theoretical Analysis

MedKoo Cat#: 558019

Name: K 259-2

CAS#: 102819-46-5

Chemical Formula: C21H18O7

Exact Mass: 382.1100

Molecular Weight: 382.37

Elemental Analysis: C, 65.97; H, 4.75; O, 29.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
K259-2; K 259-2; K 2592
IUPAC/Chemical Name
1,6,8-Trihydroxy-3-[(Z)-2-ethyl-2-butenyl]-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid
InChi Key
SYTAMFWHVQWAKV-OQFOIZHKSA-N
InChi Code
1S/C21H18O7/c1-3-9(4-2)5-10-6-12-17(19(25)15(10)21(27)28)20(26)16-13(18(12)24)7-11(22)8-14(16)23/h3,6-8,22-23,25H,4-5H2,1-2H3,(H,27,28)/b9-3-
SMILES Code
c1(c(c(cc2C(c3cc(cc(c3C(c12)=O)O)O)=O)C\C(=C/C)CC)C(=O)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 382.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen JW, Li X, Zhao HM. [Analysis of vitamins and inorganic elements in the water extracts of Radix Changii]. Zhong Xi Yi Jie He Xue Bao. 2004 Sep;2(5):379-81. Chinese. PubMed PMID: 15383265. 2: Matsuda Y, Nakanishi S, Nagasawa K, Kase H. Inhibition by new anthraquinone compounds, K-259-2 and KS-619-1, of calmodulin-dependent cyclic nucleotide phosphodiesterase. Biochem Pharmacol. 1990 Mar 1;39(5):841-9. PubMed PMID: 2155616. 3: Yasuzawa T, Yoshida M, Shirahata K, Sano H. Structure of a novel Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase inhibitor K-259-2. J Antibiot (Tokyo). 1987 Aug;40(8):1101-3. PubMed PMID: 3680021. 4: Matsuda Y, Asano K, Kawamoto I, Kase H. K-259-2, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase from Micromonospora olivasterospora. J Antibiot (Tokyo). 1987 Aug;40(8):1092-100. PubMed PMID: 3680020.