MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 341461 | Name: Flumetsulam

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Flumetsulam is a biochemical.

Chemical Structure

Flumetsulam
Flumetsulam
CAS#98967-40-9

Theoretical Analysis

MedKoo Cat#: 341461

Name: Flumetsulam

CAS#: 98967-40-9

Chemical Formula: C12H9F2N5O2S

Exact Mass: 325.0445

Molecular Weight: 325.29

Elemental Analysis: C, 44.31; H, 2.79; F, 11.68; N, 21.53; O, 9.84; S, 9.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Flumetsulam; XRD-498; XRD 498; XRD498.
IUPAC/Chemical Name
(1,2,4)Triazolo(1,5-a)pyrimidine-2-sulfonamide, N-(2,6-difluorophenyl)-5-methyl-
InChi Key
RXCPQSJAVKGONC-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H9F2N5O2S/c1-7-5-6-19-11(15-7)16-12(17-19)22(20,21)18-10-8(13)3-2-4-9(10)14/h2-6,18H,1H3
SMILES Code
O=S(C1=NN2C=CC(C)=NC2=N1)(NC3=C(F)C=CC=C3F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 325.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li KJ, Qu RY, Liu YC, Yang JF, Devendar P, Chen Q, Niu CW, Xi Z, Yang GF. Design, Synthesis, and Herbicidal Activity of Pyrimidine-Biphenyl Hybrids as Novel Acetohydroxyacid Synthase Inhibitors. J Agric Food Chem. 2018 Apr 18;66(15):3773-3782. doi: 10.1021/acs.jafc.8b00665. Epub 2018 Apr 10. PubMed PMID: 29618205. 2: Li J, Li M, Gao X, Fang F. A novel amino acid substitution Trp574Arg in acetolactate synthase (ALS) confers broad resistance to ALS-inhibiting herbicides in crabgrass (Digitaria sanguinalis). Pest Manag Sci. 2017 Dec;73(12):2538-2543. doi: 10.1002/ps.4651. Epub 2017 Aug 18. PubMed PMID: 28643897. 3: Palma G, Jorquera M, Demanet R, Elgueta S, Briceño G, de la Luz Mora M. Urea Fertilizer and pH Influence on Sorption Process of Flumetsulam and MCPA Acidic Herbicides in a Volcanic Soil. J Environ Qual. 2016 Jan;45(1):323-30. doi: 10.2134/jeq2015.07.0358. PubMed PMID: 26828188. 4: Zhong M, Wang T, Hu J. Dissipation kinetics and residues of triazolopyrimidine herbicides flumetsulam and florasulam in corn ecosystem. Environ Monit Assess. 2015 Jun;187(6):390. doi: 10.1007/s10661-015-4593-4. Epub 2015 May 31. PubMed PMID: 26026845. 5: Deng W, Cao Y, Yang Q, Liu MJ, Mei Y, Zheng MQ. Different cross-resistance patterns to AHAS herbicides of two tribenuron-methyl resistant flixweed (Descurainiasophia L.) biotypes in China. Pestic Biochem Physiol. 2014 Jun;112:26-32. doi: 10.1016/j.pestbp.2014.05.003. Epub 2014 Jun 2. PubMed PMID: 24974114. 6: Chen Y, Hu J, Yang T. Dissipation and residues of flumetsulam in wheat and soil. Bull Environ Contam Toxicol. 2012 Jun;88(6):897-901. doi: 10.1007/s00128-012-0601-3. Epub 2012 Mar 30. PubMed PMID: 22460803. 7: Struger J, Grabuski J, Cagampan S, Rondeau M, Sverko E, Marvin C. Occurrence and distribution of sulfonylurea and related herbicides in central Canadian surface waters 2006-2008. Bull Environ Contam Toxicol. 2011 Oct;87(4):420-5. doi: 10.1007/s00128-011-0361-5. Epub 2011 Jul 27. PubMed PMID: 21792538. 8: Lang ZF, Shen JJ, Cai S, Zhang J, He J, Li SP. Expression, characterization, and site-directed mutation of a multiple herbicide-resistant acetohydroxyacid synthase (rAHAS) from Pseudomonas sp. Lm10. Curr Microbiol. 2011 Aug;63(2):145-50. doi: 10.1007/s00284-011-9953-x. Epub 2011 Jun 3. PubMed PMID: 21638043. 9: Liu X, Xu J, Li Y, Dong F, Li J, Song W, Zheng Y. Rapid residue analysis of four triazolopyrimidine herbicides in soil, water, and wheat by ultra-performance liquid chromatography coupled to tandem mass spectrometry. Anal Bioanal Chem. 2011 Mar;399(7):2539-47. doi: 10.1007/s00216-010-4606-7. Epub 2011 Jan 8. PubMed PMID: 21221546. 10: Chen CN, Chen Q, Liu YC, Zhu XL, Niu CW, Xi Z, Yang GF. Syntheses and herbicidal activity of new triazolopyrimidine-2-sulfonamides as acetohydroxyacid synthase inhibitor. Bioorg Med Chem. 2010 Jul 15;18(14):4897-904. doi: 10.1016/j.bmc.2010.06.015. Epub 2010 Jun 11. PubMed PMID: 20598554. 11: Chen CN, Lv LL, Ji FQ, Chen Q, Xu H, Niu CW, Xi Z, Yang GF. Design and synthesis of N-2,6-difluorophenyl-5-methoxyl-1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamide as acetohydroxyacid synthase inhibitor. Bioorg Med Chem. 2009 Apr 15;17(8):3011-7. doi: 10.1016/j.bmc.2009.03.018. Epub 2009 Mar 14. PubMed PMID: 19342247. 12: Sun X, Huang X, Chen B, Li S, He J. [Isolation of a metsulfuron-methyl-resistant bacteria and cloning and expression of the acetohydroxyacid synthase genes ilvlH]. Wei Sheng Wu Xue Bao. 2008 Nov;48(11):1493-8. Chinese. PubMed PMID: 19149165. 13: Albert-García JR, Icardo MC, Calatayud JM. Analytical strategy photodegradation/chemiluminescence/continuous-flow multicommutation methodology for the determination of the herbicide Propanil. Talanta. 2006 May 15;69(3):608-14. doi: 10.1016/j.talanta.2005.10.044. Epub 2005 Dec 15. PubMed PMID: 18970611. 14: Xu H, Pan W, Song D, Yang G. Development of an improved liquid phase microextraction technique and its application in the analysis of flumetsulam and its two analogous herbicides in soil. J Agric Food Chem. 2007 Nov 14;55(23):9351-6. Epub 2007 Oct 23. PubMed PMID: 17953444. 15: Rodriguez-Delgado MA, Hernández-Borges J. Rapid analysis of triazolopyrimidine sulfoanilide herbicides in waters and soils by high-performance liquid chromatography with UV detection using a C18 monolithic column. J Sep Sci. 2007 Jan;30(1):8-14. PubMed PMID: 17313135. 16: Moawad M, Khoo CS. Liquid chromatographic determination of flumetsulam in soybeans. J AOAC Int. 2005 Sep-Oct;88(5):1463-8. PubMed PMID: 16385997. 17: Hernández-Borges J, García-Montelongo FJ, Cifuentes A, Rodríguez-Delgado MA. Analysis of triazolopyrimidine herbicides in soils using field-enhanced sample injection-coelectroosmotic capillary electrophoresis combined with solid-phase extraction. J Chromatogr A. 2005 Dec 30;1100(2):236-42. Epub 2005 Oct 5. PubMed PMID: 16212970. 18: Hernández-Borges J, Rodriguez-Delgado MA, García-Montelongo FJ, Cifuentes A. Analysis of pesticides in soy milk combining solid-phase extraction and capillary electrophoresis-mass spectrometry. J Sep Sci. 2005 Jun;28(9-10):948-56. PubMed PMID: 16013821. 19: Hernández-Borges J, García-Montelongo FJ, Cifuentes A, Rodríguez-Delgado MA. Determination of herbicides in mineral and stagnant waters at ng/L levels using capillary electrophoresis and UV detection combined with solid-phase extraction and sample stacking. J Chromatogr A. 2005 Apr 8;1070(1-2):171-7. PubMed PMID: 15861801. 20: Spadotto CA, Hornsby AG, Gomes MA. Sorption and leaching potential of acidic herbicides in Brazilian soils. J Environ Sci Health B. 2005;40(1):29-37. PubMed PMID: 15656159.