MedKoo Cat#: 571631 | Name: BS3-d4 Deuterated Crosslinker
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BS3-d4 Deuterated Crosslinker, or Bis(Sulfosuccinimidyl) 2,2,7,7-suberate-d4, is a water soluble and membrane impermeable, protein crosslinking agent with four deuterium atoms to provide a four dalton shift by mass spectrometry.

Chemical Structure

BS3-d4 Deuterated Crosslinker
BS3-d4 Deuterated Crosslinker
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 571631

Name: BS3-d4 Deuterated Crosslinker

CAS#: NONE

Chemical Formula: C16H14D4N2Na2O14S2

Exact Mass: 576.0246

Molecular Weight: 576.44

Elemental Analysis: C, 33.34; H, 3.85; N, 4.86; Na, 7.98; O, 38.86; S, 11.12

Price and Availability

Size Price Availability Quantity
10mg USD 385.00 2 Weeks
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Related CAS #
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Synonym
BS3-d4, BS3-d4 Deuterated Crosslinker, Deuterated Crosslinker BS3-d4, D4-BS3
IUPAC/Chemical Name
Suberic acid-2,2,7,7-d4 bis (3-sulfo-N-hydroxysuccinimide ester) disodium salt
InChi Key
MGJYOHMBGJPESL-JVDLJEIDSA-L
InChi Code
InChI=1S/C16H20N2O14S2.2Na/c19-11-7-9(33(25,26)27)15(23)17(11)31-13(21)5-3-1-2-4-6-14(22)32-18-12(20)8-10(16(18)24)34(28,29)30;;/h9-10H,1-8H2,(H,25,26,27)(H,28,29,30);;/q;2*+1/p-2/i5D2,6D2;;
SMILES Code
O=C(ON1C(CC(S(=O)([O-])=O)C1=O)=O)C([2H])([2H])CCCCC([2H])([2H])C(ON2C(CC(S(=O)([O-])=O)C2=O)=O)=O.[Na+].[Na+]
Appearance
Solid powder
Purity
>89% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Mass shifts are readily observed when heavy BS3-d4 is used in combination with the non-deuterated light BS3 crosslinking analog (BS3-d0) for mass spec studies.
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 576.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Haladová K, Mrázek H, Ječmen T, Halada P, Man P, Novák P, Chmelík J, Obšil T, Šulc M. The combination of hydrogen/deuterium exchange or chemical cross-linking techniques with mass spectrometry: mapping of human 14-3-3ζ homodimer interface. J Struct Biol. 2012 Jul;179(1):10-7. doi: 10.1016/j.jsb.2012.04.016. Epub 2012 May 2. PubMed PMID: 22580067.