Synonym
CDI Crosslinker, N,N'-Carbonyldiimidazole, 1,1'-Carbonyldiimidazole
IUPAC/Chemical Name
1,1'-Carbonyldiimidazole
InChi Key
PFKFTWBEEFSNDU-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
SMILES Code
O=C(N1C=CN=C1)N2C=CN=C2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
162.15
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Koch H, Hammer N, Ossmann S, Schierle K, Sack U, Hofmann J, Wecks M, Boldt A. Tissue Engineering of Ureteral Grafts: Preparation of Biocompatible Crosslinked Ureteral Scaffolds of Porcine Origin. Front Bioeng Biotechnol. 2015 Jun 23;3:89. doi: 10.3389/fbioe.2015.00089. eCollection 2015. PubMed PMID: 26157796; PubMed Central PMCID: PMC4477215.
2: Qazvini NT, Zinatloo S. Synthesis and characterization of gelatin nanoparticles using CDI/NHS as a non-toxic cross-linking system. J Mater Sci Mater Med. 2011 Jan;22(1):63-9. doi: 10.1007/s10856-010-4178-2. Epub 2010 Nov 4. PubMed PMID: 21052793.
3: Zhu J, Heng Y, Zhang D, Wen Y, Li H, Zhao G. Synthesis and characterization of enzymatically cross-linked feruloyl amylopectin for curcumin encapsulation. Int J Biol Macromol. 2016 Apr;85:126-32. doi: 10.1016/j.ijbiomac.2015.12.073. Epub 2015 Dec 28. PubMed PMID: 26730483.
4: Hage C, Iacobucci C, Rehkamp A, Arlt C, Sinz A. The First Zero-Length Mass Spectrometry-Cleavable Cross-Linker for Protein Structure Analysis. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14551-14555. doi: 10.1002/anie.201708273. Epub 2017 Oct 9. PubMed PMID: 28876504.
