Sulfo-SANPAH Crosslinker | CAS# 102568-43-4 | Crosslinker

MedKoo Cat#: 571615 | Name: Sulfo-SANPAH Crosslinker

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfo-SANPAH Crosslinker, or N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate is a water soluble, heterobifunctional protein crosslinker with a spacer arm length of 18.2 angstroms.

Chemical Structure

Sulfo-SANPAH Crosslinker

CAS#102568-43-4

Theoretical Analysis

MedKoo Cat#: 571615

Name: Sulfo-SANPAH Crosslinker

CAS#: 102568-43-4

Chemical Formula: C16H19N6O9S

Exact Mass: 471.0934

Molecular Weight: 471.42

Elemental Analysis: C, 40.77; H, 4.06; N, 17.83; O, 30.54; S, 6.80

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 400.00
1g	USD 2,150.00

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

Sulfo-SANPAH Crosslinker, Sulfo-SANPAH Cross linker, Sulfo-SANPAH Cross-linker

IUPAC/Chemical Name

N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate

InChi Key

PSPGTVVVZNJURU-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H19N6O9S/c17-20-19-11-5-6-12(13(10-11)21(26)27)18-9-3-1-2-4-16(25)31-22(32(28,29)30)14(23)7-8-15(22)24/h5-6,10,18H,1-4,7-9H2,(H,28,29,30)

SMILES Code

O=C(O[N]1(S(=O)(O)=O)C(CCC1=O)=O)CCCCCNC2=CC=C(N=[N+]=[N-])C=C2[N+]([O-])=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

The Sulfo-SANPAH crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups. Sulfo-SANPAH crosslinker is immediately water soluble without the use of organic solvents. Commonly, Sulfo-SANPAH enhances Western blot experiments; likewise Sulfo-SANPAH activated polyacrylamide (PAA) gel crosslinked to fibronectin or collagen extracellular matrix (ECM) is used in tissue culture studies.

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 471.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Lee, H. H., Lee, H. C., Chou, C. C., Hur, S. S., Osterday, K., del Álamo, J. C., ... & Chien, S. (2013). Shp2 plays a crucial role in cell structural orientation and force polarity in response to matrix rigidity. Proceedings of the National Academy of Sciences, 110(8), 2840-2845. Vonwil, D., Trüssel, A., Haupt, O., Gobaa, S., Barbero, A., Shastri, V. P., & Martin, I. (2012). Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes. Drug Delivery and Translational Research, 2(5), 351-362. Al-Haque, S., Miklas, J. W., Feric, N., Chiu, L. L., Chen, W. L. K., Simmons, C. A., & Radisic, M. (2012). Hydrogel Substrate Stiffness and Topography Interact to Induce Contact Guidance in Cardiac Fibroblasts. Macromolecular bioscience, 12(10), 1342-1353.