MedKoo Cat#: 562561 | Name: AH-3960
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AH-3960 is an agonist of thyroid hormone receptor-1 (PTHR1).

Chemical Structure

AH-3960
AH-3960
CAS#862907-48-0

Theoretical Analysis

MedKoo Cat#: 562561

Name: AH-3960

CAS#: 862907-48-0

Chemical Formula: C13H22N4O3

Exact Mass: 282.1692

Molecular Weight: 282.34

Elemental Analysis: C, 55.30; H, 7.85; N, 19.84; O, 17.00

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 7,850.00 2 Weeks
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Related CAS #
No Data
Synonym
AH-3960; AH 3960; AH3960;
IUPAC/Chemical Name
1,3-Dibutyl-5-(diaminomethylidene)-1,3-diazinane-2,4,6-trione
InChi Key
KTVAHYZLKKQAOW-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H22N4O3/c1-3-5-7-16-11(18)9(10(14)15)12(19)17(13(16)20)8-6-4-2/h3-8,14-15H2,1-2H3
SMILES Code
O=C(N(CCCC)C(/C1=C(N)\N)=O)N(CCCC)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 282.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Carter PH, Dean T, Bhayana B, Khatri A, Rajur R, Gardella TJ. Actions of the small molecule ligands SW106 and AH-3960 on the type-1 parathyroid hormone receptor. Mol Endocrinol. 2015 Feb;29(2):307-21. doi: 10.1210/me.2014-1129. Epub 2015 Jan 13. PubMed PMID: 25584411; PubMed Central PMCID: PMC4318877. 2: Rickard DJ, Wang FL, Rodriguez-Rojas AM, Wu Z, Trice WJ, Hoffman SJ, Votta B, Stroup GB, Kumar S, Nuttall ME. Intermittent treatment with parathyroid hormone (PTH) as well as a non-peptide small molecule agonist of the PTH1 receptor inhibits adipocyte differentiation in human bone marrow stromal cells. Bone. 2006 Dec;39(6):1361-72. Epub 2006 Aug 10. PubMed PMID: 16904389.