MedKoo Cat#: 562532 | Name: DBIBB
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DBIBB is a LPA2 receptor-specific nonlipid agonist. It acts by mitigating cell and tissue injury in vitro and in vivo, protecting cells from radiation injury and enhancing DNA repair via LPA2.

Chemical Structure

DBIBB
DBIBB
CAS#1569309-92-7

Theoretical Analysis

MedKoo Cat#: 562532

Name: DBIBB

CAS#: 1569309-92-7

Chemical Formula: C23H20N2O6S

Exact Mass: 452.1042

Molecular Weight: 452.48

Elemental Analysis: C, 61.05; H, 4.46; N, 6.19; O, 21.22; S, 7.09

Price and Availability

Size Price Availability Quantity
5mg USD 425.00 2 Weeks
10mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
DBIBB;
IUPAC/Chemical Name
2-[4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butylsulfamoyl]-benzoic acid
InChi Key
POLJNARIJSROOS-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H20N2O6S/c26-21-17-10-5-7-15-8-6-11-18(20(15)17)22(27)25(21)14-4-3-13-24-32(30,31)19-12-2-1-9-16(19)23(28)29/h1-2,5-12,24H,3-4,13-14H2,(H,28,29)
SMILES Code
O=C(O)C1=CC=CC=C1S(=O)(NCCCCN(C(C2=CC=CC3=CC=CC4=C23)=O)C4=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 452.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Lin, F.T., Lai, Y.J., Makarova, N., et al. The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival. The Journal of Biological Chemisty 282(52), 37759-37769 (2007). 2. Patil, R., Szabó, E., Fells, J.I., et al. Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist. Chemistry & Biology 22, 206-216 (2015).