MedKoo Cat#: 527864 | Name: EcDsbB-IN-9

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EcDsbB-IN-9 is a novel specific inhibitor of EcDsbB, targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria.

Chemical Structure

EcDsbB-IN-9
EcDsbB-IN-9
CAS#41933-33-9

Theoretical Analysis

MedKoo Cat#: 527864

Name: EcDsbB-IN-9

CAS#: 41933-33-9

Chemical Formula: C11H8Cl2N2O

Exact Mass: 254.0014

Molecular Weight: 255.10

Elemental Analysis: C, 51.79; H, 3.16; Cl, 27.79; N, 10.98; O, 6.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
EcDsbBIN9; EcDsbB IN 9; EcDsbB-IN-9
IUPAC/Chemical Name
4,5-Dichloro-2-benzylpyridazin-3(2H)-one
InChi Key
AJHBQZQCDCTOFD-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H8Cl2N2O/c12-9-6-14-15(11(16)10(9)13)7-8-4-2-1-3-5-8/h1-6H,7H2
SMILES Code
O=C1C(Cl)=C(Cl)C=NN1CC2=CC=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 255.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ireland PM, McMahon RM, Marshall LE, Halili M, Furlong E, Tay S, Martin JL, Sarkar-Tyson M. Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo. Antioxid Redox Signal. 2014 Feb 1;20(4):606-17. doi: 10.1089/ars.2013.5375. Epub 2013 Sep 20. PubMed PMID: 23901809; PubMed Central PMCID: PMC3901323. 2: Shouldice SR, Heras B, Walden PM, Totsika M, Schembri MA, Martin JL. Structure and function of DsbA, a key bacterial oxidative folding catalyst. Antioxid Redox Signal. 2011 May 1;14(9):1729-60. doi: 10.1089/ars.2010.3344. Epub 2011 Jan 17. Review. PubMed PMID: 21241169.