HA-08 | potent IRAP inhibitor

MedKoo Cat#: 128425 | Name: HA-08

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HA-08 is a potent IRAP inhibitor (IC50 = 8 nM).

Chemical Structure

HA-08

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128425

Name: HA-08

CAS#: N/A

Chemical Formula: C26H32N4O6S2

Exact Mass: 560.1763

Molecular Weight: 560.68

Elemental Analysis: C, 55.70; H, 5.75; N, 9.99; O, 17.12; S, 11.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HA-08; HA08; HA 08

IUPAC/Chemical Name

2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,10-dioxo-1,2-dithia-5,9-diazacyclotridecane-4-carboxamido)methyl)phenyl)acetic acid

InChi Key

VZYRMNZEFCZSER-BVSLBCMMSA-N

InChi Code

InChI=1S/C26H32N4O6S2/c27-21-9-10-37-38-15-22(26(36)28-14-18-4-2-1-3-17(18)12-24(33)34)30-23(32)13-19(29-25(21)35)11-16-5-7-20(31)8-6-16/h1-8,19,21-22,31H,9-15,27H2,(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t19-,21-,22-/m0/s1

SMILES Code

OC1=CC=C(C[C@H](NC([C@@H](N)CCSSC[C@@H](C(NCC2=CC=CC=C2CC(O)=O)=O)N3)=O)CC3=O)C=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 560.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Fu ZG, Wang Y, Wang S, Shao D, Tian L, Li YX, Jiang JL, Chen ZN, Wen N. Synthesis and Evaluation of a Novel Small-molecule Compound as an Anticancer Inhibitor of CD147. Biomed Environ Sci. 2019 Sep;32(9):673-686. doi: 10.3967/bes2019.086. PMID: 31635683.