MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 341289 | Name: Methicillin sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methicillin sodium is a biochemical.

Chemical Structure

Methicillin sodium
Methicillin sodium
CAS#7246-14-2 (Na)

Theoretical Analysis

MedKoo Cat#: 341289

Name: Methicillin sodium

CAS#: 7246-14-2 (Na)

Chemical Formula: C17H21N2NaO7S

Exact Mass: 420.0967

Molecular Weight: 420.41

Elemental Analysis: C, 48.57; H, 5.04; N, 6.66; Na, 5.47; O, 26.64; S, 7.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
61-32-5 (free base) 7246-14-2 (Na) 132-92-3 (sodium)
Synonym
Methicillin sodium; BRL-1241; BRL1241; BRL 1241; X 1497; X-1497; X1497.
IUPAC/Chemical Name
sodium (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
InChi Key
NRZPASQBOYNGHR-HWROMZCQSA-M
InChi Code
InChI=1S/C17H20N2O6S.Na.H2O/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4;;/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23);;1H2/q;+1;/p-1/t11-,12+,15-;;/m1../s1
SMILES Code
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(OC)C=CC=C3OC)=O)N1C2=O)[O-].[H]O[H].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 420.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shrestha NK, Fraser TG, Gordon SM. Methicillin Resistance in Staphylococcus aureus Infections among Patients Colonized with Methicillin-Susceptible Staphylococcus aureus. Clin Microbiol Infect. 2018 Apr 9. pii: S1198-743X(18)30323-9. doi: 10.1016/j.cmi.2018.03.045. [Epub ahead of print] PubMed PMID: 29649598. 2: Chiew CJ, Ho HJ, Win MK, Tan A, Lim JW, Ang B, Chow A. Persistence of meticillin-resistant Staphylococcus aureus carriage in readmitted patients. J Hosp Infect. 2018 Apr 9. pii: S0195-6701(18)30213-5. doi: 10.1016/j.jhin.2018.04.001. [Epub ahead of print] PubMed PMID: 29649554. 3: Santos-Junior AG, Ferreira AM, Frota OP, Rigotti MA, Barcelos LDS, Lopes de Sousa AF, de Andrade D, Guerra OG, R Furlan MC. Effectiveness of Surface Cleaning and Disinfection in a Brazilian Healthcare Facility. Open Nurs J. 2018 Mar 28;12:36-44. doi: 10.2174/1874434601812010036. eCollection 2018. PubMed PMID: 29643951; PubMed Central PMCID: PMC5876921. 4: Wang X, Thompson CD, Weidenmaier C, Lee JC. Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform. Nat Commun. 2018 Apr 11;9(1):1379. doi: 10.1038/s41467-018-03847-z. PubMed PMID: 29643357. 5: Buttachon S, Ramos AA, Inácio Â, Dethoup T, Gales L, Lee M, Costa PM, Silva AMS, Sekeroglu N, Rocha E, Pinto MMM, Pereira JA, Kijjoa A. Bis-Indolyl Benzenoids, Hydroxypyrrolidine Derivatives and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Aspergillus candidus KUFA0062. Mar Drugs. 2018 Apr 6;16(4). pii: E119. doi: 10.3390/md16040119. PubMed PMID: 29642369. 6: Solecka J, Rajnisz A, Postek M, Laudy AE, Szawkalo J, Czarnocki Z. SYNTHETIC DERIVATIVES OF ISOQUINOLINE, DICARBOXYLIC ACID IMIDES AND THIOIMIDES AS BIOACTIVE COMPOUNDS. Acta Pol Pharm. 2016 Sep;73(5):1181-1189. PubMed PMID: 29638058. 7: Phokhaphan P, Tingpej P, Apisarnthanarak A, Kondo S. PREVALENCE AND ANTIBIOTIC SUSCEPTIBLITY OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS, COLLECTED AT THAMMASAT UNIVERSITY HOSPITAL, THAILAND, AUGUST 2012 - JULY 2015. Southeast Asian J Trop Med Public Health. 2017 Mar;48(2):351-9. PubMed PMID: 29642297. 8: Chaalal W, Chaalal N, Bourafa N, Kihal M, Diene SM, Rolain JM. Characterization of Staphylococcus aureus Isolated from Food Products in Western Algeria. Foodborne Pathog Dis. 2018 Mar 15. doi: 10.1089/fpd.2017.2339. [Epub ahead of print] PubMed PMID: 29638169. 9: Manomayitthikan T, Borlace GN, Kessomboon N. DEVELOPMENT OF AN ANTIBIOTIC OPTIONS INDEX FOR ANTIBIOTIC RESISTANCE MONITORING. Southeast Asian J Trop Med Public Health. 2016 Nov;47(6):1288-97. PubMed PMID: 29634194. 10: Juda M, Helon P, Malm A. ANTI-ADHESIVE AND ANTI-BIOFILM ACTIVITIES IN VITRO OF LINEZOLID, VANCOMYCIN, TIGECYCLINE AND DAPTOMYCIN AGAINST STAPHYLOCOCCUS HAEMOLYTICUS. Acta Pol Pharm. 2016 Nov;73(6):1539-1543. PubMed PMID: 29634108. 11: Kwon KT, Armstrong DG. Microbiology and Antimicrobial Therapy for Diabetic Foot Infections. Infect Chemother. 2018 Mar;50(1):11-20. doi: 10.3947/ic.2018.50.1.11. Review. PubMed PMID: 29637748. 12: West AM, Teska PJ, Lineback CB, Oliver HF. Strain, disinfectant, concentration, and contact time quantitatively impact disinfectant efficacy. Antimicrob Resist Infect Control. 2018 Apr 3;7:49. doi: 10.1186/s13756-018-0340-2. eCollection 2018. PubMed PMID: 29636911; PubMed Central PMCID: PMC5883281. 13: Mody L, Foxman B, Bradley S, McNamara S, Lansing B, Gibson K, Cassone M, Armbruster C, Mantey J, Min L. Longitudinal Assessment of Multidrug-Resistant Organisms in Newly Admitted Nursing Facility Patients: Implications for an Evolving Population. Clin Infect Dis. 2018 Apr 9. doi: 10.1093/cid/ciy194. [Epub ahead of print] PubMed PMID: 29635360. 14: Comparison table: some antibiotics for MRSA skin and skin structure infections. Med Lett Drugs Ther. 2018 Mar 26;60(1543):e59-e62. PubMed PMID: 29635269. 15: Delafloxacin (Baxdela)--a new fluoroquinolone antibiotic. Med Lett Drugs Ther. 2018 Mar 26;60(1543):49-51. PubMed PMID: 29635263. 16: Xu A, Hyman D, Lu LB. Cefazolin-Related Acute Interstitial Nephritis with Associated Nephrotic-Range Proteinuria: A Case Report. Drug Saf Case Rep. 2018 Apr 9;5(1):16. doi: 10.1007/s40800-018-0080-5. PubMed PMID: 29633042. 17: Myer ENB, Petrikovets A, Slocum PD, Lee TG, Carter-Brooks CM, Noor N, Carlos DM, Wu E, van Eck K, Fashokun TB, Yurteri-Kaplan L, Chen CCG. Risk factors for explantation due to infection after sacral neuromodulation: a multicenter retrospective case-control study. Am J Obstet Gynecol. 2018 Apr 6. pii: S0002-9378(18)30282-5. doi: 10.1016/j.ajog.2018.04.005. [Epub ahead of print] PubMed PMID: 29630890. 18: De Foggi CC, Ayres MSB, Feltrin GP, Jorge JH, Machado AL. Effect of surface characteristics of soft liners and tissue conditioners and saliva on the adhesion and biofilm formation. Am J Dent. 2018 Feb;31(1):45-52. PubMed PMID: 29630805. 19: Orabona GD, Corvino R, Maglitto F, Abbate V, Bonavolontà P, Romano A, Salzano G, Califano L. Infective complications after free flaps reconstruction in patients affected by head and neck cancer Our experience on 77 cases. Ann Ital Chir. 2018;89:62-65. PubMed PMID: 29629890. 20: Dayer R, Alzahrani MM, Saran N, Ouellet JA, Journeau P, Tabard-Fougère A, Martinez-Álvarez S, Ceroni D. Spinal infections in children. Bone Joint J. 2018 Apr 1;100-B(4):542-548. doi: 10.1302/0301-620X.100B4.BJJ-2017-1080.R1. PubMed PMID: 29629576.