MedKoo Cat#: 562499 | Name: Buflomedil HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Buflomedil HCl is an inhibitor of platelet aggregation. It acts by improving deformability of erythrocytes with abnormal fluidity.

Chemical Structure

Buflomedil HCl
Buflomedil HCl
CAS#35543-24-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 562499

Name: Buflomedil HCl

CAS#: 35543-24-9 (HCl)

Chemical Formula: C17H26ClNO4

Exact Mass: 343.1550

Molecular Weight: 343.84

Elemental Analysis: C, 59.38; H, 7.62; Cl, 10.31; N, 4.07; O, 18.61

Price and Availability

Size Price Availability Quantity
1g USD 265.00 2 Weeks
5g USD 550.00 2 Weeks
10g USD 850.00 2 Weeks
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Synonym
Buflomedil HCl; Buflomedil Hydrochloride; LL-1656; LL 1656; LL1656
IUPAC/Chemical Name
4-(Pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one Hydrochloride
InChi Key
ZDPACSAHMZADFZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H
SMILES Code
O=C(C1=C(OC)C=C(OC)C=C1OC)CCCN2CCCC2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 343.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: El-Desoky HS, Ghoneim MM, Abdel-Galeil MM. Quantification of the Vasoactive Agent Buflomedil HCl in Pharmaceutical Formulation and Human Serum by Stripping Voltammetry and Liquid Chromatography. Acta Chim Slov. 2010 Jun;57(2):332-40. PubMed PMID: 24061728. 2: Neri C, Barbareschi M, Turrina S, De Leo D. Suicide by buflomedil HCl: a case report. J Clin Forensic Med. 2004 Feb;11(1):15-6. PubMed PMID: 15261008. 3: Sungthongjeen S, Puttipipatkhachorn S, Paeratakul O, Dashevsky A, Bodmeier R. Development of pulsatile release tablets with swelling and rupturable layers. J Control Release. 2004 Mar 5;95(2):147-59. PubMed PMID: 14980764. 4: Dubourg A, Scamuffa RF. An experimental overview of a new vasoactive drug: buflomedil HCl. Angiology. 1981 Oct;32(10):663-75. Review. PubMed PMID: 7034590.