AR-C141990 is a MCT inhibitor (monocarboxylate transporter inhibitor). AR-C141990 inhibited brain penetration of HOCPCA in a dose-dependent manner (ID50 = 4.6 mg/kg). AR-C141990 Inhibits graft versus host response and prolongs cardiac graft survival in a rat model. Immunosuppressant. Also inhibits brain penetration of GHB analog HOCPCA.
MedKoo Cat#: 562421
Name: AR-C141990
CAS#: 873327-59-4 (free base)
Chemical Formula: C26H28N4O4S
Exact Mass: 492.1831
Molecular Weight: 492.59
Elemental Analysis: C, 63.40; H, 5.73; N, 11.37; O, 12.99; S, 6.51
The following data is based on the product molecular weight 492.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
