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MedKoo Cat#: 562379 | Name: CFM-5

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CFM-5 is an antagonist of anaphase-promoting complex (APC)-2 and cell cycle and apoptosis regulatory protein (CARP)-1 interaction.

Chemical Structure

CFM-5
CFM-5
CAS#639507-03-2

Theoretical Analysis

MedKoo Cat#: 562379

Name: CFM-5

CAS#: 639507-03-2

Chemical Formula: C23H18BrN3OS

Exact Mass: 463.0354

Molecular Weight: 464.38

Elemental Analysis: C, 59.49; H, 3.91; Br, 17.21; N, 9.05; O, 3.45; S, 6.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CFM-5; CFM 5; CFM5;
IUPAC/Chemical Name
5-Bromo-5'-phenyl-1-(2-phenylethyl)-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one
InChi Key
XNQKFLVXBADQOZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H18BrN3OS/c24-18-11-12-20-19(15-18)23(26-25-21(29-23)17-9-5-2-6-10-17)22(28)27(20)14-13-16-7-3-1-4-8-16/h1-12,15,26H,13-14H2
SMILES Code
O=C1N(CCC2=CC=CC=C2)C3=C(C=C(Br)C=C3)C14SC(C5=CC=CC=C5)=NN4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 464.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Schäper M, Reimann S, Frentzen M, Meister J. Imaging of Dental Hard Tissue Surfaces Prepared by an Ultrashort Pulsed Laser System (USPL). Microsc Microanal. 2016 Dec;22(6):1189-1197. doi: 10.1017/S1431927616012022. Epub 2016 Dec 12. PubMed PMID: 27938451. 2: Rizzo M, De Sarro G, Zappalà M, Chimirri A. Determination of new 2,3-benzodiazepines in rat plasma using high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl. 1999 Aug 20;731(2):207-15. PubMed PMID: 10510773. 3: De Sarro G, Rizzo M, Spagnolo C, Gitto R, De Sarro A, Scotto G, Zappala M, Chimirri A. Anticonvulsant activity and plasma level of 2,3-benzodiazepin-4-ones (CFMs) in genetically epilepsy-prone rats. Pharmacol Biochem Behav. 1999 Aug;63(4):621-7. PubMed PMID: 10462191. 4: Samovar AG, Orlovskaia EE. [Effect of biologically active agents on the feeding response of Dileptus anser]. Tsitologiia. 1979 Mar;21(3):340-6. Russian. PubMed PMID: 219570.

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