Ractopamine HCl | CAS#90274-24-1 | beta-Adrenergic agonist

MedKoo Cat#: 562319 | Name: Ractopamine HCl

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ractopamine HCl is a beta-Adrenergic agonist. It acts by being a full agonist at the TAAR1.

Chemical Structure

Ractopamine HCl

CAS#90274-24-1

Theoretical Analysis

MedKoo Cat#: 562319

Name: Ractopamine HCl

CAS#: 90274-24-1

Chemical Formula: C18H24ClNO3

Exact Mass: 0.0000

Molecular Weight: 337.84

Elemental Analysis: C, 63.99; H, 7.16; Cl, 10.49; N, 4.15; O, 14.21

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 285.00	2 Weeks
1g	USD 585.00	2 Weeks

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

Ractopamine HCl; Ractopamine Hydrochloride;

IUPAC/Chemical Name

4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butan-2-yl)amino)ethyl)phenol hydrochloride

InChi Key

JHGSLSLUFMZUMK-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-8-16(20)9-5-14)19-12-18(22)15-6-10-17(21)11-7-15;/h4-11,13,18-22H,2-3,12H2,1H3;1H

SMILES Code

OC1=CC=C(C=C1)C(CNC(CCC2=CC=C(C=C2)O)C)O.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 337.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: McAtee TB, Renter DG, Murphy T, Betts NB, Depenbusch BE. Cattle, carcass, economic, and estimated emission impacts of feeding finishing steers lubabegron or ractopamine hydrochloride. Transl Anim Sci. 2024 Mar 8;8:txae031. doi: 10.1093/tas/txae031. PMID: 38707257; PMCID: PMC11067785. 2: Spears JW, Loh HY, Lloyd KE, Heldt JS, Engle TE. Trace mineral source and chromium propionate supplementation affect performance and carcass characteristics in feedlot steers. J Anim Sci. 2024 Jan 3;102:skae106. doi: 10.1093/jas/skae106. PMID: 38613515; PMCID: PMC11067787. 3: Pfau AP, Henniger MT, Samuelson KL, Hales KE, Löest CA, Hubbert ME, Lindholm- Perry AK, Egert-McLean AM, Mason KM, Shepherd EA, Voy BH, Myer PR. Effects of protein concentration and beta-adrenergic agonists on ruminal bacterial communities in finishing beef heifers. PLoS One. 2024 Feb 29;19(2):e0296407. doi: 10.1371/journal.pone.0296407. PMID: 38422047; PMCID: PMC10903865. 4: Reeves Pitts MA, Smith HR, Amerson EC, Starkey JD, Starkey CW, Sawyer JT, Brandebourg TD. Feeding Ractopamine Improves the Growth Performance and Carcass Characteristics of the Lard-Type Mangalica Pig. Animals (Basel). 2023 Dec 15;13(24):3857. doi: 10.3390/ani13243857. PMID: 38136893; PMCID: PMC10740923. 5: Pfau AP, Shepherd EA, Martin MG, Ascolese S, Mason KM, Egert-McLean AM, Voy BH, Myer PR. Beta-Adrenergic Agonists, Dietary Protein, and Rumen Bacterial Community Interactions in Beef Cattle: A Review. Vet Sci. 2023 Sep 18;10(9):579. doi: 10.3390/vetsci10090579. PMID: 37756100; PMCID: PMC10537598. 6: Gubbels ER, Rusche WC, Block E, Rehberger T, Thomson JS, Smith ZK. Evaluation of long-term supplementation of a direct-fed microbial and enzymatically hydrolyzed yeast cell culture product on feedlot growth performance, efficiency of dietary net energy utilization, heat stress measures, and carcass characteristics in beef steers. Transl Anim Sci. 2023 Feb 3;7(1):txad016. doi: 10.1093/tas/txad016. PMID: 36845361; PMCID: PMC9951183. 7: Rients EL, Deters EL, McGill JL, Belknap CR, Hansen SL. Effects of feeding a Saccharomyces cerevisiae fermentation product and ractopamine hydrochloride to finishing beef steers on growth performance, immune system, and muscle gene expression. J Anim Sci. 2023 Jan 3;101:skac311. doi: 10.1093/jas/skac311. PMID: 36592754; PMCID: PMC9831109. 8: Soares MH, Júnior DTV, de Amorim Rodrigues G, Júnior RLC, Rocha GC, Bohrer BM, Juárez M, de Souza Duarte M, Saraiva A. Effects of feeding ractopamine hydrochloride with or without supplemental betaine on live performance, carcass and meat quality traits, and gene expression of finishing pigs. Meat Sci. 2022 Sep;191:108851. doi: 10.1016/j.meatsci.2022.108851. Epub 2022 May 17. PMID: 35598425. 9: Messersmith EM, Smerchek DT, Hansen SL. Effects of increasing supplemental zinc in beef feedlot steers administered a steroidal implant and beta agonist. Transl Anim Sci. 2022 Feb 28;6(2):txac029. doi: 10.1093/tas/txac029. PMID: 35382158; PMCID: PMC8974338. 10: Harsh BN, Klatt BJ, Volk MJ, Green-Miller AR, McCann JC. Effects of ractopamine hydrochloride on nutrient digestibility and nitrogen excretion of finishing beef cattle. Transl Anim Sci. 2021 Mar 7;5(2):txab036. doi: 10.1093/tas/txab036. PMID: 34853827; PMCID: PMC8628867. 11: Messersmith E, Branine M, Genther-Schroeder O, McGill J, Hansen S. Initial Liver Copper Status in Finishing Beef Steers Fed Three Dietary Concentrations of Copper Affects Beta Agonist Performance, Carcass Characteristics, Lipolysis Response, and Muscle Inflammation Markers. Animals (Basel). 2021 Sep 21;11(9):2753. doi: 10.3390/ani11092753. PMID: 34573719; PMCID: PMC8465330. 12: Valenzuela-Grijalva N, Jiménez-Estrada I, Mariscal-Tovar S, López-García K, Pinelli-Saavedra A, Peña-Ramos EA, Muhlia-Almazán A, Zamorano-García L, Valenzuela-Melendres M, González-Ríos H. Effects of Ferulic Acid Supplementation on Growth Performance, Carcass Traits and Histochemical Characteristics of Muscle Fibers in Finishing Pigs. Animals (Basel). 2021 Aug 20;11(8):2455. doi: 10.3390/ani11082455. PMID: 34438911; PMCID: PMC8388683. 13: Hwang JH, Spurlock ME, Kube JC, Li XZ, Smith SB. Characterization of β-adrenergic receptors in bovine intramuscular and subcutaneous adipose tissue: comparison of lubabegron fumarate with β-adrenergic receptor agonists and antagonists. J Anim Sci. 2021 Aug 1;99(8):skab116. doi: 10.1093/jas/skab116. PMID: 34337647; PMCID: PMC8326056. 14: Rincker PJ, Allen JB, Edmonds M, Brown MS, Kube JC. Effects of voluntary removal of ractopamine hydrochloride (Optaflexx) on live performance and carcass characteristics of beef steers. Transl Anim Sci. 2021 Mar 9;5(2):txab047. doi: 10.1093/tas/txab047. PMID: 34124588; PMCID: PMC8191484. 15: Ross EG, Ball JJ, Werth SJ, Mejia-Turcios SE, Zhao Y, Pan Y, Taube PC, Meinert TR, Van Engen NK, Mitloehner FM. Effect of ractopamine hydrochloride on environmental gas emissions, growth performance, and carcass characteristics in feedlot steers. J Anim Sci. 2021 May 1;99(5):skab143. doi: 10.1093/jas/skab143. PMID: 33939826; PMCID: PMC8153700. 16: Engel CL, Tibbetts G, Branine ME. Influence of feeding amino acid complexes of zinc and copper on growth performance and carcass response of finishing steers fed ractopamine hydrochloride. Transl Anim Sci. 2020 Dec 22;4(Suppl 1):S122-S126. doi: 10.1093/tas/txaa118. PMID: 33381734; PMCID: PMC7754241. 17: Davis HE, Geornaras I, Lindstrom V, Chaparro JM, Nair MN, Delmore RJ, Engle TE, Belk KE, Prenni JE. Effects of differing withdrawal times from ractopamine hydrochloride on residue concentrations of beef muscle, adipose tissue, rendered tallow, and large intestine. PLoS One. 2020 Dec 2;15(12):e0242673. doi: 10.1371/journal.pone.0242673. PMID: 33264353; PMCID: PMC7710041. 18: Needham T, Gous RM, Lambrechts H, Pieterse E, Hoffman LC. Combined Effect of Dietary Protein, Ractopamine, and Immunocastration on Boar Taint Compounds, and Using Testicle Parameters as an Indicator of Success. Foods. 2020 Nov 14;9(11):1665. doi: 10.3390/foods9111665. PMID: 33202637; PMCID: PMC7698110. 19: Smith ZK, Renter DG, Holland BP, Word AB, Crawford GI, Nichols WT, Nuttelman BL, Streeter MN, Walter LJ, Hutcheson JP, Dicke B, Brandt RT Jr, Szasz JI, Bryant TC, Pringle LFG, Carlson ZE, Erickson GE, Johnson BJ. A pooled analysis of six large-pen feedlot studies: effects of a noncoated initial and terminal implant compared with a single initial and delayed-release implant on arrival in feedlot heifers. Transl Anim Sci. 2020 Jul 2;4(3):txaa109. doi: 10.1093/tas/txaa109. PMID: 32728660; PMCID: PMC7377577. 20: DeClerck JC, Lucherk LW, Reeves NR, Miller MF, Bernhard BC, Rathmann RJ. Influence of ractopamine hydrochloride and days on feed on feedlot performance and red meat yield in thin cull beef cows targeted for a lean market. Transl Anim Sci. 2019 Dec 4;4(1):170-181. doi: 10.1093/tas/txz184. PMID: 32704977; PMCID: PMC6994039.