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MedKoo Cat#: 527775 | Name: BBMP

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BBMP is a mitochondrial permeability transition pore (PTP) inhibitor.

Chemical Structure

BBMP
BBMP
CAS#97120-13-3

Theoretical Analysis

MedKoo Cat#: 527775

Name: BBMP

CAS#: 97120-13-3

Chemical Formula: C12H11BrN2O3S

Exact Mass: 341.9674

Molecular Weight: 343.20

Elemental Analysis: C, 42.00; H, 3.23; Br, 23.28; N, 8.16; O, 13.99; S, 9.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
BBMP
IUPAC/Chemical Name
5-Benzylsulfonyl-4-bromo-2-methylpyridazin-3-one
InChi Key
ICJYBAMRYLSLQT-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H11BrN2O3S/c1-15-12(16)11(13)10(7-14-15)19(17,18)8-9-5-3-2-4-6-9/h2-7H,8H2,1H3
SMILES Code
O=C1C(Br)=C(S(=O)(CC2=CC=CC=C2)=O)C=NN1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 343.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Bifunctional bacterial magnetic nanoparticles for tumor targeting. Nanoscale. 2012 Feb 7;4(3):879-84. doi: 10.1039/c2nr11407k. Epub 2012 Jan 4. PubMed PMID: 22218728. 7: Sepioł J, Grabowska A, Borowicz P, Kijak M, Broquier M, Jouvet Ch, Dedonder-Lardeux C, Zehnacker-Rentien A. Excited-state intramolecular proton transfer reaction modulated by low-frequency vibrations: an effect of an electron-donating substituent on the dually fluorescent bis-benzoxazole. J Chem Phys. 2011 Jul 21;135(3):034307. doi: 10.1063/1.3609759. PubMed PMID: 21787003. 8: Pan W, Wei Y, Zhou L, Li D. Comparative in vivo study of injectable biomaterials combined with BMP for enhancing tendon graft osteointegration for anterior cruciate ligament reconstruction. J Orthop Res. 2011 Jul;29(7):1015-21. doi: 10.1002/jor.21351. Epub 2011 Feb 9. PubMed PMID: 21308754. 9: Zoń J, Kong D, Gagnon K, Perry H, Holliness L, Clearfield A. Supramolecular networks of polymethylphosphonic acid groups bonded to aromatic platforms: biphenyldiyl-2,2'-bis(methylphosphonic acid) and benzenetriyl-1,3,5-tris(methylphosphonic acid). Dalton Trans. 2010 Dec 7;39(45):11008-18. doi: 10.1039/c0dt00676a. Epub 2010 Oct 20. PubMed PMID: 20963215. 10: Casado PL, Duarte ME, Carvalho W, Esmeraldo da Silva L, Barboza EP. Ridge bone maintenance in human after extraction. Implant Dent. 2010 Aug;19(4):314-22. doi: 10.1097/ID.0b013e3181dec322. PubMed PMID: 20683288. 11: Adli M, Garipagaoglu M, Kocak Z. Effect of bladder distention on bladder base dose in gynaecological intracavitary high dose rate brachytherapy. Br J Radiol. 2009 Mar;82(975):243-8. doi: 10.1259/bjr/90233932. Epub 2008 Dec 8. PubMed PMID: 19064593. 12: Ma X, Hu Y, Wu X, Yan Y, Xiong Z, Lu R, Wang J, Li D, Xu X. [Surface modification of biodegradable polymer/TCP scaffolds and related research]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2008 Jun;25(3):571-7. Chinese. 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Repair of the radial defect of rabbit with polyester/tricalcium phosphate scaffolds prepared by rapid prototyping technology. Chin J Traumatol. 2006 Oct;9(5):298-302. PubMed PMID: 17026863. 18: Serra E Silva FM, Ricardo de Albergaria-Barbosa J, Mazzonetto R. Clinical evaluation of association of bovine organic osseous matrix and bovine bone morphogenetic protein versus autogenous bone graft in sinus floor augmentation. J Oral Maxillofac Surg. 2006 Jun;64(6):931-5. PubMed PMID: 16713808. 19: Fuks B, Talaga P, Huart C, Hénichart JP, Bertrand K, Grimée R, Lorent G. In vitro properties of 5-(benzylsulfonyl)-4-bromo-2-methyl-3(2H)-pyridazinone: a novel permeability transition pore inhibitor. Eur J Pharmacol. 2005 Sep 5;519(1-2):24-30. PubMed PMID: 16099453. 20: Sun L, Hu YY, Xiong Z, Wang WM, Pan Y. [Repair of the radial defect of rabbit by polyester/tricalcium phosphate scaffolds prepared by rapid prototyping technology]. Zhonghua Wai Ke Za Zhi. 2005 Apr 15;43(8):535-9. Chinese. PubMed PMID: 15938915.

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