BVT-116429 | CAS#870710-02-4 | 11β-HSD1 inhibitor

MedKoo Cat#: 562275 | Name: BVT-116429

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BVT-116429 is a 11β-HSD1 inhibitor.

Chemical Structure

BVT-116429

CAS#870710-02-4

Theoretical Analysis

MedKoo Cat#: 562275

Name: BVT-116429

CAS#: 870710-02-4

Chemical Formula: C13H12F4N2OS

Exact Mass: 320.0606

Molecular Weight: 320.30

Elemental Analysis: C, 48.75; H, 3.78; F, 23.73; N, 8.75; O, 4.99; S, 10.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

BVT-116429; BVT 116429; BVT116429;

IUPAC/Chemical Name

(5S)-2-[[(1S)-1-(2-Fluorophenyl)ethyl]amino]-5-methyl-5-(trifluoromethyl)-4(5H)-thiazolone

InChi Key

KNHNFKZUNFPPQE-MADCSZMMSA-N

InChi Code

InChI=1S/C13H12F4N2OS/c1-7(8-5-3-4-6-9(8)14)18-11-19-10(20)12(2,21-11)13(15,16)17/h3-7H,1-2H3,(H,18,19,20)/t7-,12-/m0/s1

SMILES Code

O=C1N=C(N[C@H](C2=CC=CC=C2F)C)S[C@]1(C)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 320.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sundbom M, Kaiser C, Björkstrand E, Castro VM, Larsson C, Selén G, Nyhem CS, James SR. Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice. BMC Pharmacol. 2008 Feb 12;8:3. doi: 10.1186/1471-2210-8-3. PubMed PMID: 18269730; PubMed Central PMCID: PMC2270815.