Synonym
Farinomalein; Farinomalein A;
IUPAC/Chemical Name
3-(3-isopropyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid
InChi Key
UWAZSQUZHSRNTR-UHFFFAOYSA-N
InChi Code
1S/C10H13NO4/c1-6(2)7-5-8(12)11(10(7)15)4-3-9(13)14/h5-6H,3-4H2,1-2H3,(H,13,14)
SMILES Code
CC(C)C1=CC(=O)N(CCC(O)=O)C1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
211.22
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Putri SP, Kinoshita H, Ihara F, Igarashi Y, Nihira T. Farinomalein, a maleimide-bearing compound from the entomopathogenic fungus Paecilomyces farinosus. J Nat Prod. 2009 Aug;72(8):1544-6. doi: 10.1021/np9002806. PMID: 19670877.
2: Nakayama A, Yasuno Y, Yamamoto Y, Saito K, Kitsuwa K, Okamura H, Shinada T. Stereoselective Syntheses of trans-Anhydromevalonic Acid and trans-Anhydromevalonyl Group-Containing Natural Products. J Nat Prod. 2022 Apr 22;85(4):1052-1058. doi: 10.1021/acs.jnatprod.1c01176. Epub 2022 Feb 23. PMID: 35195424.
3: Chen Y, Zhang L, Zou G, Li C, Yang W, Liu H, She Z. Anti-inflammatory activities of alkaloids from the mangrove endophytic fungus Phomopsis sp. SYSUQYP-23. Bioorg Chem. 2020 Apr;97:103712. doi: 10.1016/j.bioorg.2020.103712. Epub 2020 Feb 28. PMID: 32146180.
4: Putri SP, Ishido K, Kinoshita H, Kitani S, Ihara F, Sakihama Y, Igarashi Y, Nihira T. Production of antioomycete compounds active against the phytopathogens Phytophthora sojae and Aphanomyces cochlioides by clavicipitoid entomopathogenic fungi. J Biosci Bioeng. 2014 May;117(5):557-62. doi: 10.1016/j.jbiosc.2013.10.014. Epub 2013 Nov 21. PMID: 24268864.