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MedKoo Cat#: 562250 | Name: Caramiphen free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Caramiphen free base is an antimuscarinic and anticholinergic agent. It acts as an antagonist of NMDA receptor.

Chemical Structure

Caramiphen free base
Caramiphen free base
CAS#77-22-5 (free base)

Theoretical Analysis

MedKoo Cat#: 562250

Name: Caramiphen free base

CAS#: 77-22-5 (free base)

Chemical Formula: C18H27NO2

Exact Mass: 289.2042

Molecular Weight: 289.41

Elemental Analysis: C, 74.70; H, 9.40; N, 4.84; O, 11.06

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
77-22-5 (free base) 125-85-9 (HCl)
Synonym
Caramiphen free base
IUPAC/Chemical Name
2-(Diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate
InChi Key
OFAIGZWCDGNZGT-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3
SMILES Code
O=C(C1(C2=CC=CC=C2)CCCC1)OCCN(CC)CC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 289.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Raveh L, Eisenkraft A, Weissman BA. Caramiphen edisylate: an optimal antidote against organophosphate poisoning. Toxicology. 2014 Nov 5;325:115-24. doi: 10.1016/j.tox.2014.09.005. Epub 2014 Sep 6. Review. PubMed PMID: 25201353. 2: Weissman BA, Raveh L. Multifunctional drugs as novel antidotes for organophosphates' poisoning. Toxicology. 2011 Dec 18;290(2-3):149-55. doi: 10.1016/j.tox.2011.09.004. Epub 2011 Sep 28. Review. PubMed PMID: 21978866. 3: Myhrer T. Identification of neuronal target areas for nerve agents and specification of receptors for pharmacological treatment. Neurotoxicology. 2010 Dec;31(6):629-38. doi: 10.1016/j.neuro.2010.07.002. Epub 2010 Jul 17. Review. PubMed PMID: 20624420. 4: Kawaura K, Honda S, Soeda F, Shirasaki T, Takahama K. [Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats]. Yakugaku Zasshi. 2010 May;130(5):699-705. Review. Japanese. PubMed PMID: 20460867. 5: Weissman BA, Raveh L. Therapy against organophosphate poisoning: the importance of anticholinergic drugs with antiglutamatergic properties. Toxicol Appl Pharmacol. 2008 Oct 15;232(2):351-8. doi: 10.1016/j.taap.2008.07.005. Epub 2008 Jul 18. Review. PubMed PMID: 18680758. 6: Gavend M, Mallaret M, Dematteis M, Baragatti G. Discriminative stimulus properties of dextromethorphan in rats. Biomed Pharmacother. 1995;49(10):456-64. Review. PubMed PMID: 8746072. 7: Musacchio JM, Klein M. Dextromethorphan binding sites in the guinea pig brain. Cell Mol Neurobiol. 1988 Jun;8(2):149-56. Review. PubMed PMID: 3044591. 8: Musacchio JM, Klein M, Santiago LJ. Allosteric modulation of dextromethorphan binding sites. Neuropharmacology. 1987 Jul;26(7B):997-1001. Review. PubMed PMID: 2821439. 9: Irwin RS, Curley FJ, Pratter MR. The effects of drugs on cough. Eur J Respir Dis Suppl. 1987;153:173-81. Review. PubMed PMID: 3322860.