MedKoo Cat#: 581111 | Name: Netzahualcoyone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Netzahualcoyone, the activity of netzahualcoyone on Bacillus subtilis and Escherichia coli was studied. The product inhibited the respiration of intact cells of B. subtilis but had no effect on the respiration of E. coli. However, when preparations of sonically disrupted cells were examined, inhibitory activity on both bacteria was observed.

Chemical Structure

Netzahualcoyone
Netzahualcoyone
CAS#87686-36-0

Theoretical Analysis

MedKoo Cat#: 581111

Name: Netzahualcoyone

CAS#: 87686-36-0

Chemical Formula: C30H36O6

Exact Mass: 492.2512

Molecular Weight: 492.61

Elemental Analysis: C, 73.15; H, 7.37; O, 19.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Netzahualcoyone;
IUPAC/Chemical Name
methyl (2R,3S,4aR,12bR,14aR,14bR)-3,10-dihydroxy-2,4a,6,9,12b,14a-hexamethyl-4,11-dioxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate
InChi Key
JBKXDADFFNVBTG-NUCARWLASA-N
InChi Code
InChI=1S/C30H36O6/c1-15-13-29(5)21(14-30(6,26(35)36-7)25(34)24(29)33)28(4)11-10-27(3)18(22(15)28)9-8-17-16(2)23(32)20(31)12-19(17)27/h8-9,12,21,25,32,34H,10-11,13-14H2,1-7H3/t21-,25-,27+,28-,29-,30-/m1/s1
SMILES Code
C1(C(=C(C2=CC=C3[C@@](CC[C@@]4(C)C3=C(C)C[C@@]3([C@@H]4C[C@@]([C@@H](C3=O)O)(C)C(=O)OC)C)(C)C2=C1)C)O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 492.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Moujir L, Gutiérrez-Navarro AM, González AG, Ravelo AG, Luis JG. Mode of action of netzahualcoyone. Antimicrob Agents Chemother. 1991 Jan;35(1):211-3. PubMed PMID: 1901699; PubMed Central PMCID: PMC244973. 2: Jeller AH, Silva DH, Lião LM, Bolzani Vda S, Furlan M. Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum. Phytochemistry. 2004 Jul;65(13):1977-82. PubMed PMID: 15280004.