MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 581100 | Name: Bauerenol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bauerenol is a triterpenoid from Indian Suregada angustifolia, is isolated from the stem bark of Acronychia pedunculata., Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. Bauerenol is an Antitrypanosomal Agent.

Chemical Structure

Bauerenol
Bauerenol
CAS#6466-94-0

Theoretical Analysis

MedKoo Cat#: 581100

Name: Bauerenol

CAS#: 6466-94-0

Chemical Formula: C30H50O

Exact Mass: 426.7290

Molecular Weight: 426.39

Elemental Analysis: C, 84.44; H, 11.81; O, 3.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Bauerenol; Baurenol; EINECS 229-283-0; NSC 147745;
IUPAC/Chemical Name
(3R,4aR,6bR,8aR,11R,12S,12aR,12bR,14aR,14bR)-4,4,6b,8a,11,12,12b,14b-octamethyl-1,2,3,4,4a,5,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicen-3-ol
InChi Key
TZVDWGXUGGUMCE-WXRCDFDUSA-N
InChi Code
InChI=1S/C30H50O/c1-19-11-14-27(5)17-18-29(7)22-9-10-23-26(3,4)24(31)13-15-28(23,6)21(22)12-16-30(29,8)25(27)20(19)2/h9,19-21,23-25,31H,10-18H2,1-8H3/t19-,20+,21+,23+,24-,25-,27-,28-,29+,30-/m1/s1
SMILES Code
C[C@@]12CC[C@](CC[C@@H](C)[C@@H]3C)(C)[C@@H]3[C@@]1(C)CC[C@@H]4[C@](CC[C@H](C5(C)C)O)(C)[C@H]5CC=C42
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 426.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li JJ, Wang AL, Yuan ZZ, Wu CY, Yang LH, Shang XY. [Triterpene compounds of Ainsliaea yunnanensis]. Zhongguo Zhong Yao Za Zhi. 2013 Nov;38(22):3918-22. Chinese. PubMed PMID: 24558876. 2: Sathish Kumar P, Viswanathan MBG, Venkatesan M, Balakrishna K. Bauerenol, a triterpenoid from Indian Suregada angustifolia: Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. Tumour Biol. 2017 Apr;39(4):1010428317698387. doi: 10.1177/1010428317698387. PubMed PMID: 28443465. 3: Ragasa CY, Espineli DL, Agoo EM, Del Fierro RS. Chemical constituents of Cinnamomum cebuense. Chin J Nat Med. 2013 May;11(3):264-8. doi: 10.1016/S1875-5364(13)60026-6. PubMed PMID: 23725839. 4: Anyanwu GO, Nisar-ur-Rehman, Onyeneke CE, Rauf K. Medicinal plants of the genus Anthocleista--A review of their ethnobotany, phytochemistry and pharmacology. J Ethnopharmacol. 2015 Dec 4;175:648-67. doi: 10.1016/j.jep.2015.09.032. Epub 2015 Nov 11. Review. PubMed PMID: 26432351. 5: Shi HM, Long BS, Cui XM, Min ZD. A new bisabolane sesquiterpenoid from Euphorbia chrysocoma. J Asian Nat Prod Res. 2005 Dec;7(6):857-60. PubMed PMID: 16308205. 6: Raga DD, Herrera AA, Ragasa CY. Angio-suppressive triterpenoids from Ardisia cf. elliptica (subgenus Tinus) on duck (Anas platyrynchos L.) chorioallantoic membrane. Chin J Nat Med. 2013 Mar;11(2):128-38. doi: 10.1016/S1875-5364(13)60039-4. PubMed PMID: 23787179. 7: Deng Y, Lu CY, Guo DL, Mei L. [Studies on the chemical constituents of Ardisia tenera]. Zhong Yao Cai. 2011 Mar;34(3):380-3. Chinese. PubMed PMID: 21823453. 8: Zhou FX, Min ZD. [Studies on the chemical constituents of Acronychia pedunculata (L.) Mig]. Zhongguo Zhong Yao Za Zhi. 1989 Feb;14(2):30-1, 62. Chinese. PubMed PMID: 2506892. 9: Fang XP, Wang TZ, Zhang H, Shuai H, Li D, Xie CK. [Quantitative determination of 5 alkaloids in plants of Coptis from China]. Zhongguo Zhong Yao Za Zhi. 1989 Feb;14(2):33-5, 63. Chinese. PubMed PMID: 2506894. 10: Yu KY, Wu W, Li SZ, Dou LL, Liu LL, Li P, Liu EH. A new compound, methylbergenin along with eight known compounds with cytotoxicity and anti-inflammatory activity from Ardisia japonica. Nat Prod Res. 2017 Nov;31(22):2581-2586. doi: 10.1080/14786419.2017.1283495. Epub 2017 Jan 30. PubMed PMID: 28135873. 11: Carothers S, Nyamwihura R, Collins J, Zhang H, Park H, Setzer WN, Ogungbe IV. Bauerenol Acetate, the Pentacyclic Triterpenoid from Tabernaemontana longipes, is an Antitrypanosomal Agent. Molecules. 2018 Feb 8;23(2). pii: E355. doi: 10.3390/molecules23020355. PubMed PMID: 29419735.

View History

Lysine aspartate

Lysine aspartate