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MedKoo Cat#: 341126 | Name: Antibiotic YC 17

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Antibiotic YC 17 is a biochemical.

Chemical Structure

Antibiotic YC 17
CAS#11091-33-1

Theoretical Analysis

MedKoo Cat#: 341126

Name: Antibiotic YC 17

CAS#: 11091-33-1

Chemical Formula: C25H43NO6

Exact Mass: 453.3090

Molecular Weight: 453.62

Elemental Analysis: C, 66.20; H, 9.56; N, 3.09; O, 21.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Antibiotic YC 17; YC-17; YC 17; YC17.
IUPAC/Chemical Name
Antibiotic YC 17
InChi Key
DZGHWPQKGWXOHD-OVPZILDZSA-N
InChi Code
InChI=1S/C25H43NO6/c1-9-21-14(2)10-11-20(27)15(3)12-16(4)23(18(6)24(29)31-21)32-25-22(28)19(26(7)8)13-17(5)30-25/h10-11,14-19,21-23,25,28H,9,12-13H2,1-8H3/b11-10-/t14-,15-,16+,17-,18-,19+,21-,22-,23+,25+/m1/s1
SMILES Code
C1[C@H](N(C)C)[C@H]([C@@H](O[C@@H]1C)O[C@@H]1[C@H](C(=O)O[C@@H]([C@@H](C=CC([C@@H](C[C@@H]1C)C)=O)C)CC)C)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 453.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shinde PB, Han AR, Cho J, Lee SR, Ban YH, Yoo YJ, Kim EJ, Kim E, Song MC, Park JW, Lee DG, Yoon YJ. Combinatorial biosynthesis and antibacterial evaluation of glycosylated derivatives of 12-membered macrolide antibiotic YC-17. J Biotechnol. 2013 Oct 20;168(2):142-8. doi: 10.1016/j.jbiotec.2013.05.014. Epub 2013 Jun 13. PubMed PMID: 23770075. 2: Rettedal E, Vilain S, Lindblom S, Lehnert K, Scofield C, George S, Clay S, Kaushik RS, Rosa AJ, Francis D, Brözel VS. Alteration of the ileal microbiota of weanling piglets by the growth-promoting antibiotic chlortetracycline. Appl Environ Microbiol. 2009 Sep;75(17):5489-95. doi: 10.1128/AEM.02220-08. Epub 2009 Jul 17. PubMed PMID: 19617391; PubMed Central PMCID: PMC2737922. 3: Podust LM, Kim Y, Arase M, Neely BA, Beck BJ, Bach H, Sherman DH, Lamb DC, Kelly SL, Waterman MR. The 1.92-A structure of Streptomyces coelicolor A3(2) CYP154C1. A new monooxygenase that functionalizes macrolide ring systems. J Biol Chem. 2003 Apr 4;278(14):12214-21. Epub 2003 Jan 7. PubMed PMID: 12519772. 4: Wilson DJ, Xue Y, Reynolds KA, Sherman DH. Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae. J Bacteriol. 2001 Jun;183(11):3468-75. PubMed PMID: 11344155; PubMed Central PMCID: PMC99645. 5: Graziani EI, Cane DE, Betlach MC, Kealey JT, McDaniel R. Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3117-20. PubMed PMID: 9873687. 6: Xue Y, Wilson D, Zhao L, Liu Hw, Sherman DH. Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae. Chem Biol. 1998 Nov;5(11):661-7. PubMed PMID: 9831532. 7: Kang MH, Won SM, Park SS, Kim SG, Novak RF, Kim ND. Piperine effects on the expression of P4502E1, P4502B and P4501A in rat. Xenobiotica. 1994 Dec;24(12):1195-204. PubMed PMID: 7771106. 8: Savino JA, Agarwal N, Wry P, Policastro A, Cerabona T, Austria L. Routine prophylactic antifungal agents (clotrimazole, ketoconazole, and nystatin) in nontransplant/nonburned critically ill surgical and trauma patients. J Trauma. 1994 Jan;36(1):20-5; discussion 25-6. PubMed PMID: 8295245.