Pin1 inhibitor API-1 | CAS#680622-70-2 | Pin1 inhibitor

MedKoo Cat#: 562195 | Name: Pin1 inhibitor API-1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pin1 inhibitor API-1 is a Pin1 inhibitor. It acts by regulating microRNA biogenesis and suppressing hepatocellular carcinoma development.

Chemical Structure

Pin1 inhibitor API-1

CAS#680622-70-2

Theoretical Analysis

MedKoo Cat#: 562195

Name: Pin1 inhibitor API-1

CAS#: 680622-70-2

Chemical Formula: C15H13F3N6O2

Exact Mass: 366.1052

Molecular Weight: 366.30

Elemental Analysis: C, 49.18; H, 3.58; F, 15.56; N, 22.94; O, 8.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Pin1 inhibitor API-1; Pin1 inhibitor API1; Pin1 inhibitor API 1;

IUPAC/Chemical Name

N-(4-(((2-Amino-9H-purin-6-yl)oxy)methyl)benzyl)-2,2,2-trifluoroacetamide

InChi Key

AQFWAWXGBQPBIA-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H13F3N6O2/c16-15(17,18)13(25)20-5-8-1-3-9(4-2-8)6-26-12-10-11(22-7-21-10)23-14(19)24-12/h1-4,7H,5-6H2,(H,20,25)(H3,19,21,22,23,24)

SMILES Code

O=C(NCC1=CC=C(COC2=C3N=CNC3=NC(N)=N2)C=C1)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 366.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pu W, Li J, Zheng Y, Shen X, Fan X, Zhou JK, He J, Deng Y, Liu X, Wang C, Yang S, Chen Q, Liu L, Zhang G, Wei YQ, Peng Y. Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development. Hepatology. 2018 Jan 30. doi: 10.1002/hep.29819. [Epub ahead of print] PubMed PMID: 29381806.