SCH-336 is a potent and selective human cannabinoid (hCB2) inverse agonist. SCH-336 is an inverse agonist at hCB2, as shown by its ability to decrease GTPgammaS binding to membranes containing hCB2, by the ability of GTPgammaS to left-shift SCH-336 binding to hCB2 in these membranes, and by the compound's ability to increase forskolin-stimulated cAMP levels in CHO cells expressing hCB2.
MedKoo Cat#: 555160
Name: SCH-336
CAS#: 447459-51-0
Chemical Formula: C23H25NO8S3
Exact Mass: 539.0742
Molecular Weight: 539.63
Elemental Analysis: C, 51.19; H, 4.67; N, 2.60; O, 23.72; S, 17.82
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 54.0 | 100.00 |
The following data is based on the product molecular weight 539.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
