MedKoo Cat#: 581074 | Name: Indapamide hemihydrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Indapamide Hemihydrate (Sandoz) is a medicine containing the active ingredient(s) indapamide. Indapamide belongs to the family of medications called diuretics ("water pills"). It is used alone or in combination with other medications to treat mild to moderate high blood pressure. This medication works by making the body lose excess water and salt.

Chemical Structure

Indapamide hemihydrate
Indapamide hemihydrate
CAS#180004-24-4(hemihydrate)

Theoretical Analysis

MedKoo Cat#: 581074

Name: Indapamide hemihydrate

CAS#: 180004-24-4(hemihydrate)

Chemical Formula: C51H64

Exact Mass:

Molecular Weight: 677.07

Elemental Analysis: C, 90.47; H, 9.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Indapamide hemihydrate; Indapamide hydrate; D06401; Tenaxil; UNII-W0LY35K007;
IUPAC/Chemical Name
4-Chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide hydrate (2:1)
InChi Key
XIOIJYRXFJJOQC-UHFFFAOYSA-N
InChi Code
InChI=1S/2C24H28.C3H8/c2*1-16-11-12-19(15-23(16)24(4,5)6)17(2)14-22-18(3)13-20-9-7-8-10-21(20)22;1-3-2/h2*7-12,15,18,22H,2,4-5,13-14H2,1,3,6H3;3H2,1-2H3
SMILES Code
C=C(CC1C(C)CC2=C1C=CC=C2)C3=CC=C(C)C(C(=C)(C)=C)=C3.C=C(CC4C(C)CC5=C4C=CC=C5)C6=CC=C(C)C(C(=C)(C)=C)=C6.CCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 677.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Antovska P, Ugarkovic S, Petruševski G, Stefanova B, Manchevska B, Petkovska R, Makreski P. Development and experimental design of a novel controlled-release matrix tablet formulation for indapamide hemihydrate. Pharm Dev Technol. 2017 Nov;22(7):851-859. doi: 10.3109/10837450.2015.1089898. Epub 2015 Sep 24. PubMed PMID: 26402027.