AZD2906 is selective glucocorticoid receptor (GR) agonist. AZD2906, was found to increase the incidence of micronucleated immature erythrocytes (MIE) in the bone marrow of rats given two oral doses at the maximum tolerated level. AZD2906 showed no activity in the standard in vitro tests or in vivo in a rat liver comet assay, investigative studies were performed to compare AZD2906 with a reference traditional GR agonist, prednisolone.
MedKoo Cat#: 555156
Name: AZD2906
CAS#: 1034148-15-6
Chemical Formula: C26H25FN4O3
Exact Mass: 460.1911
Molecular Weight: 460.51
Elemental Analysis: C, 67.81; H, 5.47; F, 4.13; N, 12.17; O, 10.42
The following data is based on the product molecular weight 460.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
