IUPAC/Chemical Name
Acetic acid, 2-(((2-amino-5-chlorophenyl)-phenylmethylidene)amino)guanidine
InChi Key
ZLUWQWGEHWFLRC-OKOHOLKASA-N
InChi Code
InChI=1S/C14H14ClN5.C2H4O2/c15-10-6-7-12(16)11(8-10)13(19-20-14(17)18)9-4-2-1-3-5-9;1-2(3)4/h1-8H,16H2,(H4,17,18,20);1H3,(H,3,4)/b19-13-;
SMILES Code
C(C)(=O)O.N(\N=C(\c1ccccc1)c1c(ccc(c1)Cl)N)C(=N)N
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
347.80
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Bubner M, Kasbohm K, Heise KH, Richter PH. [Anti-arrhythmic actions of amidinohydrazone substituted benzophenones. 7. Synthesis of C14 labeled (Z)- and (E)-2-amino-5-chlorbenzophenonamidinohydrazone]. Pharmazie. 1995 Jan;50(1):71-2. German. PubMed PMID: 7886129.
2: Schleuder M, Keckeis A, Richter PH, Jira T. [Anti-arrhythmia action of amidinohydrazone substituted benzophenones. 6. Parenteral drug forms of (Z)-2-amino-5-chlorobenzophenone amidinohydrazone acetate (G 256)]. Pharmazie. 1994 Sep;49(9):653-6. German. PubMed PMID: 7972310.
3: Volkmann H, Dannberg G, Kühnert H, Hoffmann A, Marschner JP, Reimann I, Farker K. [Hemodynamic effects and adverse effects of the anti-arrhythmic substance AWD-G256 in man]. Pharmazie. 1993 May;48(5):385-7. German. PubMed PMID: 8327569.
4: Volkmann H, Hoffmann A, Kühnert H, Dannberg G, Heinke M, Reimann I, Marschner JP, Farker K. [Clinical-electrophysiologic studies on the actions of the anti-arrhythmic substance AWD-G256 in man]. Pharmazie. 1993 May;48(5):380-5. German. PubMed PMID: 8327568.
5: Farker K, Henschel L, Marschner JP, Reimann I, Volkmann H, Hoffmann A. [The pharmacokinetics of a new anti-arrhythmic substance, Z-2-amino-5-chlorobenzophenoneamidinohydrazone (AWD-G256)]. Pharmazie. 1993 May;48(5):373-80. German. PubMed PMID: 8327567.
6: Schieweck A, offchert HH, Morgenroth U, Joram U. [The pharmacokinetics of Z-2-amino-5-chlorobenzophenoneamidinohydrazone in the rat]. Pharmazie. 1993 May;48(5):370-3. German. PubMed PMID: 8327566.
7: Borchert HH, Schieweck A, Franke P, Morgenroth U, Joram U. [Biotransformation and excretion of Z-2-amino-5-chlorobenzophenoneamidinohydrazone]. Pharmazie. 1993 May;48(5):365-70. German. PubMed PMID: 8327565.
8: Schleuder M, Richter PH, Keckeis A, Jira T. [Antiarrhythmia active amidinohydrazone substituted benzophenones. 5. The stability of (Z)-2-amino-5-chlorobenzophenone amidinohydrazone acetate in solution]. Pharmazie. 1993 Jan;48(1):33-7. German. PubMed PMID: 8460174.
