MedKoo Cat#: 562054 | Name: GA11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GA11 inhibitor of ALDH1. It also shows anti-GBM effects in vitro and in vivo.

Chemical Structure

GA11
GA11
CAS#851053-64-0

Theoretical Analysis

MedKoo Cat#: 562054

Name: GA11

CAS#: 851053-64-0

Chemical Formula: C19H14N2

Exact Mass: 270.1157

Molecular Weight: 270.33

Elemental Analysis: C, 84.42; H, 5.22; N, 10.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
GA11; GA-11; GA 11;
IUPAC/Chemical Name
2,6-Diphenyl-imidazo[1,2-a]pyridine
InChi Key
LETMYYZWCFHZLY-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H14N2/c1-3-7-15(8-4-1)17-11-12-19-20-18(14-21(19)13-17)16-9-5-2-6-10-16/h1-14H
SMILES Code
C12=NC(C3=CC=CC=C3)=CN1C=C(C4=CC=CC=C4)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 270.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Institute for Quality and Efficiency in Health Care. Stem Cell Transplantation for Multiple Myeloma -- Update [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2015 Mar 30. Available from http://www.ncbi.nlm.nih.gov/books/NBK385769/ PubMed PMID: 28609086. 2: Cheng P, Wang J, Waghmare I, Sartini S, Coviello V, Zhang Z, Kim SH, Mohyeldin A, Pavlyukov MS, Minata M, Valentim CL, Chhipa RR, Bhat KP, Dasgupta B, La Motta C, Kango-Singh M, Nakano I. FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells. Cancer Res. 2016 Dec 15;76(24):7219-7230. Epub 2016 Aug 28. PubMed PMID: 27569208; PubMed Central PMCID: PMC5161538. 3: Briceño G, Schalchli H, Rubilar O, Tortella GR, Mutis A, Benimeli CS, Palma G, Diez MC. Increased diazinon hydrolysis to 2-isopropyl-6-methyl-4-pyrimidinol in liquid medium by a specific Streptomyces mixed culture. Chemosphere. 2016 Aug;156:195-203. doi: 10.1016/j.chemosphere.2016.04.118. Epub 2016 May 10. PubMed PMID: 27176942. 4: Steenbergen KG, Gaston N. First-principles melting of gallium clusters down to nine atoms: structural and electronic contributions to melting. Phys Chem Chem Phys. 2013 Oct 7;15(37):15325-32. doi: 10.1039/c3cp51690c. PubMed PMID: 23764996. 5: Föllner CG, Madkour M, Mayer F, Babel W, Steinbüchel A. Analysis of the PHA granule-associated proteins GA20 and GA11 in Methylobacterium extorquens and Methylobacterium rhodesianum. J Basic Microbiol. 1997;37(1):11-21. PubMed PMID: 9090123. 6: Saing KM, Orii H, Tanaka Y, Yanagisawa K, Miura A, Ikeda H. Formation of deletion in Escherichia coli between direct repeats located in the long inverted repeats of a cellular slime mold plasmid: participation of DNA gyrase. Mol Gen Genet. 1988 Sep;214(1):1-5. PubMed PMID: 2852300.