Palatrigine | CAS#98410-36-7 | antiarrhythmic

MedKoo Cat#: 584315 | Name: Palatrigine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Palatrigine, also known as BW A256C, is a chemically novel agent which exhibits in a single molecule both angiotensin converting enzyme (ACE) inhibition and beta-adrenoceptor-blocking properties.

Chemical Structure

Palatrigine

CAS#98410-36-7

Theoretical Analysis

MedKoo Cat#: 584315

Name: Palatrigine

CAS#: 98410-36-7

Chemical Formula: C12H13Cl2N5

Exact Mass: 297.0548

Molecular Weight: 298.17

Elemental Analysis: C, 48.34; H, 4.39; Cl, 23.78; N, 23.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Palatrigine ; BW A256C; BW-A 256C

IUPAC/Chemical Name

1,2,4-Triazin-3-amine, 2,5-dihydro-6-(2,3-dichlorophenyl)-5-imino-2-(1-methylethyl)-

InChi Key

XJQJAFGEQVKYNF-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H13Cl2N5/c1-6(2)19-12(16)17-11(15)10(18-19)7-4-3-5-8(13)9(7)14/h3-6H,1-2H3,(H3,15,16,17)

SMILES Code

NC(N(C(C)C)N=C1C2=CC=CC(Cl)=C2Cl)=NC1=N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 298.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Allan G, Donoghue S, Follenfant MJ, Sawyer DA. BW A256C, a chemically novel class 1 antiarrhythmic agent. A comparison of in vitro and in vivo activity with other class 1 antiarrhythmic agents. Br J Pharmacol. 1986 Jun;88(2):333-43. PubMed PMID: 3730698; PubMed Central PMCID: PMC1916834. 2: Donoghue S, Payne PN, Allan G. Effects of BW A256C, a novel class 1 antiarrhythmic agent, on maximum rate of depolarisation of cardiac action potentials in vitro: frequency, use, and voltage dependence. J Cardiovasc Pharmacol. 1987 Jan;9(1):12-8. PubMed PMID: 2434786. 3: Allan G, Cambridge D, Hardy GW, Follenfant MJ. BW A575C, a chemically novel agent with angiotensin converting enzyme inhibitor and beta-adrenoceptor-blocking properties. Br J Pharmacol. 1987 Mar;90(3):609-15. PubMed PMID: 2882805; PubMed Central PMCID: PMC1917187.