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MedKoo Cat#: 527600 | Name: Mutant IDH1-IN-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mutant IDH1-IN-1 is a novel IDH1-Mutant inhibitor.

Chemical Structure

Mutant IDH1-IN-1
Mutant IDH1-IN-1
CAS#1355326-21-4

Theoretical Analysis

MedKoo Cat#: 527600

Name: Mutant IDH1-IN-1

CAS#: 1355326-21-4

Chemical Formula: C30H31FN4O2

Exact Mass: 498.2431

Molecular Weight: 498.60

Elemental Analysis: C, 72.27; H, 6.27; F, 3.81; N, 11.24; O, 6.42

Price and Availability

Size Price Availability Quantity
5mg USD 355.00 2 Weeks
10mg USD 585.00 2 Weeks
25mg USD 1,075.00 2 Weeks
50mg USD 1,750.00 2 Weeks
100mg USD 2,250.00 2 Weeks
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Related CAS #
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Synonym
Mutant IDH1-IN-1
IUPAC/Chemical Name
2-(N-[2-(Benzimidazol-1-yl)acetyl]-3-fluoroanilino)-N-cyclohexyl-2-(2-methylphenyl)acetamide
InChi Key
DXYIOARJXVTYJW-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H31FN4O2/c1-21-10-5-6-15-25(21)29(30(37)33-23-12-3-2-4-13-23)35(24-14-9-11-22(31)18-24)28(36)19-34-20-32-26-16-7-8-17-27(26)34/h5-11,14-18,20,23,29H,2-4,12-13,19H2,1H3,(H,33,37)
SMILES Code
O=C(NC1CCCCC1)C(N(C(CN2C3=CC=CC=C3N=C2)=O)C4=CC=CC(F)=C4)C5=CC=CC=C5C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 498.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 29333130; PubMed Central PMCID: PMC5763090. 10: Gupta R, Thakur R, Kushwaha S, Jalan N, Rawat P, Gupta P, Aggarwal A, Gupta M, Manchanda V. Isoniazid and rifampicin heteroresistant Mycobacterium tuberculosis isolated from tuberculous meningitis patients in India. Indian J Tuberc. 2018 Jan;65(1):52-56. doi: 10.1016/j.ijtb.2017.08.005. Epub 2017 Aug 14. PubMed PMID: 29332649. 11: Pfab A, Breindl M, Grasser KD. The Arabidopsis histone chaperone FACT is required for stress-induced expression of anthocyanin biosynthetic genes. Plant Mol Biol. 2018 Jan 13. doi: 10.1007/s11103-018-0701-5. [Epub ahead of print] PubMed PMID: 29332189. 12: Arner A, Rockenstein E, Mante M, Florio J, Masliah D, Salehi B, Adame A, Overk C, Masliah E, Rissman RA. Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau. J Alzheimers Dis. 2018;61(3):1201-1219. doi: 10.3233/JAD-170388. 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