Synonym
Anetholtrithion; Anethole trithione; ADT; Trithio-p-methoxyphenylpropene; SKF 1717; SKF-1717; SKF1717; Anetholdithiolthione; Anethole Dithiolthione
IUPAC/Chemical Name
3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-
InChi Key
KYLIZBIRMBGUOP-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3
SMILES Code
S=C1SSC(C2=CC=C(OC)C=C2)=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
240.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Niedermeier W, Huber M, Fischer D, Beier K, Müller N, Schuler R, Brinninger A, Fartasch M, Diepgen T, Matthaeus C, Meyer C, Hector MP. Significance of saliva for the denture-wearing population. Gerodontology. 2000 Dec;17(2):104-18. doi: 10.1111/j.1741-2358.2000.00104.x. PMID: 11808055.
2: Matsuo S, Ninomiya H, Takasiba T, Sasaki Y. Anetholtrithion stabilizes body weight fluctuation caused by excessive water drinking in a patient with schizophrenia: a case report. J Clin Psychiatry. 1999 Oct;60(10):706. doi: 10.4088/jcp.v60n1013. PMID: 10549689.
3: Goedde HW, Ohligmacher H. Taste thresholds of thiourea derivatives and anetholtrithion in twins. Acta Genet Stat Med. 1966;16(4):350-4. doi: 10.1159/000151982. PMID: 6012904.
4: Goedde HW, Ohligmacher H. Zur Problematik des Polymorphismus des Bitterschmeckens: Vergleichende Untersuchungen an Thioharnstoffderivaten und Anetholtrithion [On problems of polymorphism of bitter taste: comparative studies on thiourea derivatives and anetholetrithione]. Humangenetik. 1965;1(5):423-36. German. PMID: 5868698.
5: GMELIN R, LAGLER F. [Tolerance and excretion of anetholtrithion]. Arzneimittelforschung. 1963 Feb;13:130-3. German. PMID: 13948558.
6: PIPPIG L, SCHMITT W, BECKER G. [Research on the influence of anetholtrithion on the hemodynamics of the liver]. Arzneimittelforschung. 1962 Apr;12:383-6. German. PMID: 14486856.
7: ROETTER W. [Clinical and experimental research with Felviten (anetholtrithion)]. Med Welt. 1961 Jun 24;25:1353-5. German. PMID: 13742717.
