MedKoo Cat#: 561801 | Name: FSBA hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FSBA is a covalent inhibitor of anthrax edema factor.

Chemical Structure

FSBA hydrochloride
FSBA hydrochloride
CAS#78859-42-4

Theoretical Analysis

MedKoo Cat#: 561801

Name: FSBA hydrochloride

CAS#: 78859-42-4

Chemical Formula: C17H17ClFN5O7S

Exact Mass: 489.0521

Molecular Weight: 489.86

Elemental Analysis: C, 41.68; H, 3.50; Cl, 7.24; F, 3.88; N, 14.30; O, 22.86; S, 6.54

Price and Availability

Size Price Availability Quantity
25mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
FSBA hydrochloride; FSBA HCl
IUPAC/Chemical Name
((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl 4-(fluorosulfonyl)benzoate hydrochloride
InChi Key
ZUHVYHQVJYIHPN-KHXPSBENSA-N
InChi Code
InChI=1S/C17H16FN5O7S.ClH/c18-31(27,28)9-3-1-8(2-4-9)17(26)29-5-10-12(24)13(25)16(30-10)23-7-22-11-14(19)20-6-21-15(11)23;/h1-4,6-7,10,12-13,16,24-25H,5H2,(H2,19,20,21);1H/t10-,12-,13-,16-;/m1./s1
SMILES Code
NC1=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COC(C4=CC=C(S(=O)(F)=O)C=C4)=O)O3)C2=NC=N1.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 489.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sharma S, Mehndiratta S, Kumar S, Singh J, Bedi PM, Nepali K. Purine Analogues as Kinase Inhibitors: A Review. Recent Pat Anticancer Drug Discov. 2015;10(3):308-41. Review. PubMed PMID: 26081925. 2: Verbeek RJ, Heep A, Maurits NM, Cremer R, Hoving EW, Brouwer OF, van der Hoeven JH, Sival DA. Fetal endoscopic myelomeningocele closure preserves segmental neurological function. Dev Med Child Neurol. 2012 Jan;54(1):15-22. doi: 10.1111/j.1469-8749.2011.04148.x. Epub 2011 Nov 29. Review. PubMed PMID: 22126123. 3: Heilmeyer LM Jr, Vereb G Jr, Vereb G, Kakuk A, Szivák I. Mammalian phosphatidylinositol 4-kinases. IUBMB Life. 2003 Feb;55(2):59-65. Review. PubMed PMID: 12749687. 4: Dombrowski KE, Ke Y, Brewer KA, Kapp JA. Ecto-ATPase: an activation marker necessary for effector cell function. Immunol Rev. 1998 Feb;161:111-8. Review. PubMed PMID: 9553768. 5: Colman RW. Receptors that activate platelets. Proc Soc Exp Biol Med. 1991 Jul;197(3):242-8. Review. PubMed PMID: 1648741. 6: Colman RW. Aggregin: a platelet ADP receptor that mediates activation. FASEB J. 1990 Mar;4(5):1425-35. Review. PubMed PMID: 2407587. 7: Colman RW. Platelet receptors. Hematol Oncol Clin North Am. 1990 Feb;4(1):27-42. Review. PubMed PMID: 2155904. 8: Colman RW, Figures WR. Characteristics of an ADP receptor mediating platelet activation. Mol Cell Biochem. 1984;59(1-2):101-11. Review. PubMed PMID: 6323960.