BI-9627 is a highly potent NHE1 inhibitor with low DDI potential, excellent pharmacokinetics, and good selectivity against NHE2 and NHE3.
MedKoo Cat#: 561796
Name: BI-9627
CAS#: 1204329-34-9
Chemical Formula: C16H19F3N4O2
Exact Mass: 356.1460
Molecular Weight: 356.34
Elemental Analysis: C, 53.93; H, 5.37; F, 15.99; N, 15.72; O, 8.98
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| DMF | 10.0 | 28.06 | ||
| DMSO | 60.0 | 168.38 | ||
| DMSO:PBS (pH 7.2) (1:7) | 0.1 | 0.34 |
The following data is based on the product molecular weight 356.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
