Pyridoxine 5'-phosphate | CAS#8059-24-3 | enzyme cofactor

MedKoo Cat#: 561780 | Name: Pyridoxine 5'-phosphate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyridoxine 5'-phosphate is an enzyme cofactor in the biosynthesis of five important neurotransmitters: serotonin, dopamine, epinephrine, norepinephrine, and gamma-aminobutyric acid (GABA).

Chemical Structure

Pyridoxine 5'-phosphate

CAS#8059-24-3

Theoretical Analysis

MedKoo Cat#: 561780

Name: Pyridoxine 5'-phosphate

CAS#: 8059-24-3

Chemical Formula: C8H12NO5P

Exact Mass: 233.0453

Molecular Weight: 233.15

Elemental Analysis: C, 41.21; H, 5.19; N, 6.01; O, 34.31; P, 13.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Pyridoxine 5'-phosphate; PLP; Vitamin B6;

IUPAC/Chemical Name

(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate

InChi Key

RBCOYOYDYNXAFA-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H12NO5P/c1-5-7(4-14-15(11,12)13)3-9-6(2)8(5)10/h3,10H,4H2,1-2H3,(H2,11,12,13)

SMILES Code

O=P(O)(O)OCC1=C(C)C(O)=C(C)N=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 233.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Rosenberg J, Ischebeck T, Commichau FM. Vitamin B6 metabolism in microbes and approaches for fermentative production. Biotechnol Adv. 2017 Jan - Feb;35(1):31-40. doi: 10.1016/j.biotechadv.2016.11.004. Epub 2016 Nov 24. Review. PubMed PMID: 27890703. 2: di Salvo ML, Safo MK, Contestabile R. Biomedical aspects of pyridoxal 5'-phosphate availability. Front Biosci (Elite Ed). 2012 Jan 1;4:897-913. Review. PubMed PMID: 22201923. 3: di Salvo ML, Contestabile R, Safo MK. Vitamin B(6) salvage enzymes: mechanism, structure and regulation. Biochim Biophys Acta. 2011 Nov;1814(11):1597-608. doi: 10.1016/j.bbapap.2010.12.006. Epub 2010 Dec 20. Review. PubMed PMID: 21182989. 4: Garrido-Franco M. Pyridoxine 5'-phosphate synthase: de novo synthesis of vitamin B6 and beyond. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):92-7. Review. PubMed PMID: 12686115. 5: di Salvo ML, Safo MK, Musayev FN, Bossa F, Schirch V. Structure and mechanism of Escherichia coli pyridoxine 5'-phosphate oxidase. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):76-82. Review. PubMed PMID: 12686112.