MedKoo Cat#: 561758 | Name: HG-6-64-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

HG-6-64-1 is a selective B-Raf and mutant B-Raf inhibitor.

Chemical Structure

HG-6-64-1
HG-6-64-1
CAS#1315329-43-1

Theoretical Analysis

MedKoo Cat#: 561758

Name: HG-6-64-1

CAS#: 1315329-43-1

Chemical Formula: C32H34F3N5O2

Exact Mass: 577.2660

Molecular Weight: 577.65

Elemental Analysis: C, 66.54; H, 5.93; F, 9.87; N, 12.12; O, 5.54

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
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Synonym
HG-6-64-1; HG 6 64 1; HG6641; HG6-64-1; HMSL 10017-101-1
IUPAC/Chemical Name
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methylbenzamide
InChi Key
UMBFDGUGXMOMHX-BQYQJAHWSA-N
InChi Code
InChI=1S/C32H34F3N5O2/c1-4-39-13-15-40(16-14-39)20-25-9-10-26(18-28(25)32(33,34)35)38-31(41)23-6-5-21(2)22(17-23)7-8-24-19-37-30-27(11-12-36-30)29(24)42-3/h5-12,17-19H,4,13-16,20H2,1-3H3,(H,36,37)(H,38,41)/b8-7+
SMILES Code
O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(/C=C/C4=CN=C(NC=C5)C5=C4OC)=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 577.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wu X, Wang S, Wang C, Wu C, Zhao Z. Bioinformatics analysis identifies coagulation factor II receptor as a potential biomarker in stomach adenocarcinoma. Sci Rep. 2024 Jan 30;14(1):2468. doi: 10.1038/s41598-024-52397-6. PMID: 38291086; PMCID: PMC10827804. 2: Tian S, Liu Y, Liu P, Nomura S, Wei Y, Huang T. Development and Validation of a Comprehensive Prognostic and Depression Risk Index for Gastric Adenocarcinoma. Int J Mol Sci. 2024 Oct 7;25(19):10776. doi: 10.3390/ijms251910776. PMID: 39409106; PMCID: PMC11476876. 3: Guo A, Zhong P, Wang L, Lin X, Feng M. Prognosis and immunotherapeutic implications of molecular classification of cervical cancer based on immunophenoscore-related genes. J Biomol Struct Dyn. 2024 Sep 23:1-16. doi: 10.1080/07391102.2024.2404545. Epub ahead of print. PMID: 39308337.