N6-Allyladenosine | CAS#15763-12-9 | RNA labeling probe

MedKoo Cat#: 561737 | Name: N6-Allyladenosine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N6-Allyladenosine is an RNA labeling probe that acts through both metabolic and enzyme-assisted manners.

Chemical Structure

N6-Allyladenosine

CAS#15763-12-9

Theoretical Analysis

MedKoo Cat#: 561737

Name: N6-Allyladenosine

CAS#: 15763-12-9

Chemical Formula: C13H17N5O4

Exact Mass: 307.1281

Molecular Weight: 307.31

Elemental Analysis: C, 50.81; H, 5.58; N, 22.79; O, 20.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

N6-Allyladenosine; N6 Allyladenosine; a6A; N-Allyladenosine; N Allyladenosine;

IUPAC/Chemical Name

(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(prop-2-enylamino)purin-9-yl]oxolane-3,4-diol

InChi Key

WTYYPLSFICPDGL-QYVSTXNMSA-N

InChi Code

InChI=1S/C13H17N5O4/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(21)9(20)7(4-19)22-13/h2,5-7,9-10,13,19-21H,1,3-4H2,(H,14,15,16)/t7-,9-,10-,13-/m1/s1

SMILES Code

O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(NCC=C)N=CN=C23)[C@@H]1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 307.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Shu X, Dai Q, Wu T, Bothwell IR, Yue Y, Zhang Z, Cao J, Fei Q, Luo M, He C, Liu J. N(6)-Allyladenosine: A New Small Molecule for RNA Labeling Identified by Mutation Assay. J Am Chem Soc. 2017 Dec 6;139(48):17213-17216. doi: 10.1021/jacs.7b06837. Epub 2017 Nov 15. PubMed PMID: 29116772. 2: Dassano A, Mancuso M, Giardullo P, De Cecco L, Ciuffreda P, Santaniello E, Saran A, Dragani TA, Colombo F. N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response. Redox Biol. 2014 Mar 6;2:580-9. doi: 10.1016/j.redox.2014.03.001. eCollection 2014. PubMed PMID: 24688894; PubMed Central PMCID: PMC3969604. 3: Spector T, Beacham LM 3rd. Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides. J Biol Chem. 1975 Apr 25;250(8):3101-7. PubMed PMID: 164459.