MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 527079 | Name: DHMC

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DHMC is a selective cytotoxic to leukemic cells over normal blood cells.

Chemical Structure

DHMC
CAS#2107-77-9

Theoretical Analysis

MedKoo Cat#: 527079

Name: DHMC

CAS#: 2107-77-9

Chemical Formula: C10H8O4

Exact Mass: 192.0423

Molecular Weight: 192.17

Elemental Analysis: C, 62.50; H, 4.20; O, 33.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
DHMC
IUPAC/Chemical Name
7,8-dihydroxy-4-methylcoumarin
InChi Key
NWQBYMPNIJXFNQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H8O4/c1-5-4-8(12)14-10-6(5)2-3-7(11)9(10)13/h2-4,11,13H,1H3
SMILES Code
O=C1OC2=C(C=CC(O)=C2O)C(C)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 192.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hodges MM, Burlew CC, Acker SN, Moore EE, Roosevelt GE, Schubert A, Hill LRS, Partrick DA, Bensard D. Pediatric appendicitis: Is referral to a regional pediatric center necessary? J Trauma Acute Care Surg. 2017 Dec 28. doi: 10.1097/TA.0000000000001787. [Epub ahead of print] PubMed PMID: 29283967. 2: Gilli F, Royce DB, DiSano KD, Pachner AR. Pegylated interferon beta in the treatment of the Theiler's murine encephalomyelitis virus mouse model of multiple sclerosis. J Neuroimmunol. 2017 Dec 15;313:34-40. doi: 10.1016/j.jneuroim.2017.10.004. Epub 2017 Oct 9. PubMed PMID: 29153606. 3: Trujillo JM, Logue ME, Kunkel R, Demas CP. Off-label Usage of Absorbable Beads Containing Antibiotics for Prevention of Surgical Site Infections. Wounds. 2017 Oct;29(10):E84-E87. PubMed PMID: 29091043. 4: Gilli F, Li L, Royce DB, DiSano KD, Pachner AR. Treatment of Theiler's virus-induced demyelinating disease with teriflunomide. J Neurovirol. 2017 Dec;23(6):825-838. doi: 10.1007/s13365-017-0570-8. Epub 2017 Sep 14. PubMed PMID: 28913765. 5: Spratt KF. Point of View. Spine (Phila Pa 1976). 2017 Jun 15;42(12):930-931. doi: 10.1097/BRS.0000000000002195. PubMed PMID: 28609323. 6: Nascimento RP, Oliveira JL, Carvalho JLC, Santos WA, Pires TRC, Batatinha MJM, El-Bachá RS, Silva VDA, Costa SL. Involvement of astrocytic CYP1A1 isoform in the metabolism and toxicity of the alkaloid pyrrolizidine monocrotaline. Toxicon. 2017 Aug;134:41-49. doi: 10.1016/j.toxicon.2017.04.005. Epub 2017 Apr 8. PubMed PMID: 28400261. 7: Spratt KF. Point of View Re: PROMIS® PF CAT Outperforms the ODI and SF-36 Physical Function Domain in Spine Patients. Spine (Phila Pa 1976). 2017 Apr 10. doi: 10.1097/BRS.0000000000002195. [Epub ahead of print] PubMed PMID: 28399550. 8: Skinner JS, Volpp KG. Replacing the Affordable Care Act: Lessons From Behavioral Economics. JAMA. 2017 May 16;317(19):1951-1952. doi: 10.1001/jama.2017.4084. PubMed PMID: 28384693. 9: Abreu FB, Liu X, Tsongalis GJ. miRNA analysis in pancreatic cancer: the Dartmouth experience. Clin Chem Lab Med. 2017 May 1;55(5):755-762. doi: 10.1515/cclm-2017-0046. Review. PubMed PMID: 28343174. 10: Hampel KJ, de Abreu FB, Sidiropoulos N, Peterson JD, Tsongalis GJ. Variant call concordance between two laboratory-developed, solid tumor targeted genomic profiling assays using distinct workflows and sequencing instruments. Exp Mol Pathol. 2017 Apr;102(2):215-218. doi: 10.1016/j.yexmp.2017.02.002. Epub 2017 Feb 10. PubMed PMID: 28192086. 11: Sheen MR, Fiering S. Exploiting Uptake of Nanoparticles by Phagocytes for Cancer Treatment. Methods Mol Biol. 2017;1530:355-367. doi: 10.1007/978-1-4939-6646-2_22. PubMed PMID: 28150214. 12: Hendrickson CD, Saini S, Pothuloori A, Mecchella JN. ASSESSING REFERRALS AND IMPROVING INFORMATION AVAILABILITY FOR CONSULTATIONS IN AN ACADEMIC ENDOCRINOLOGY CLINIC. Endocr Pract. 2017 Feb;23(2):190-198. doi: 10.4158/EP161514.OR. Epub 2016 Nov 16. PubMed PMID: 27849384. 13: Kumar V, Mathur D, Srivastava S, Malhotra S, Rana N, Singh SK, Singh BK, Prasad AK, Varma AJ, Len C, Kuhad RC, Saxena RK, Parmar VS. Biocatalytic Synthesis of Novel Partial Esters of a Bioactive Dihydroxy 4-Methylcoumarin by Rhizopus oryzae Lipase (ROL). Molecules. 2016 Nov 9;21(11). pii: E1499. PubMed PMID: 27834873. 14: Toth AR, Possidente CJ, Sawyer LM, DiParlo MA, Fanciullo GJ. National and Northern New England Opioid Prescribing Patterns, 2013-2014. Pain Med. 2017 Sep 1;18(9):1706-1714. doi: 10.1093/pm/pnw231. PubMed PMID: 27794547. 15: Brown JR, McCullough PA, Matheny ME. Novel Developments in Acute Kidney Injury. Biomed Res Int. 2016;2016:2756204. doi: 10.1155/2016/2756204. Epub 2016 Aug 10. PubMed PMID: 27595099; PubMed Central PMCID: PMC4995325. 16: Kulcsar Z, Albert D, Ercolano E, Mecchella JN. Telerheumatology: A technology appropriate for virtually all. Semin Arthritis Rheum. 2016 Dec;46(3):380-385. doi: 10.1016/j.semarthrit.2016.05.013. Epub 2016 Jun 3. PubMed PMID: 27395561. 17: Alston MJ, Alexandrovic K, Stiglich N, Metz TD. Discontinuation of Tocolytics for Preterm Labor in an Academic Safety Net Hospital: Impact on the Duration of Betamethasone Exposure. J Reprod Med. 2016 Mar-Apr;61(3-4):109-13. PubMed PMID: 27172632. 18: Price J. Informed shared decision-making in planning for the end of life. Br J Nurs. 2016 Apr 14-27;25(7):378-83. doi: 10.12968/bjon.2016.25.7.378. PubMed PMID: 27081732. 19: Roth RM, Garlinghouse MA, Flashman LA, Koven NS, Pendergrass JC, Ford JC, McAllister TW, Saykin AJ. Apathy Is Associated With Ventral Striatum Volume in Schizophrenia Spectrum Disorder. J Neuropsychiatry Clin Neurosci. 2016 Summer;28(3):191-4. doi: 10.1176/appi.neuropsych.15100241. Epub 2016 Feb 22. PubMed PMID: 26900738; PubMed Central PMCID: PMC5023440. 20: Sarwar S, Khan AA, Tarique S. Response Guided Interferon Therapy for Genotype 3 of Chronic Hepatitis C: Compliance and Outcome. Pak J Med Sci. 2015 Jul-Aug;31(4):843-7. doi: 10.12669/pjms.314.7293. PubMed PMID: 26430415; PubMed Central PMCID: PMC4590361.