MedKoo Cat#: 561726 | Name: Ganoderenic Acid D
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ganoderenic Acid D is the major active component of Ganoderma lucidum, and acts by inhibiting the growth of numerous cancer cell lines.

Chemical Structure

Ganoderenic Acid D
Ganoderenic Acid D
CAS#100665-43-8

Theoretical Analysis

MedKoo Cat#: 561726

Name: Ganoderenic Acid D

CAS#: 100665-43-8

Chemical Formula: C30H40O7

Exact Mass: 512.2774

Molecular Weight: 512.64

Elemental Analysis: C, 70.29; H, 7.87; O, 21.85

Price and Availability

Size Price Availability Quantity
1mg USD 400.00 2 Weeks
5mg USD 850.00 2 Weeks
10mg USD 1,350.00 2 Weeks
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Related CAS #
No Data
Synonym
Ganoderenic Acid D; Ganoderenic-Acid D;
IUPAC/Chemical Name
(Z)-6-[(5R,7S,10S,13R,14R,17R)-7-Hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxohept-5-enoic acid
InChi Key
JGWQYLZHPPFHEH-HNXDABDESA-N
InChi Code
InChI=1S/C30H40O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h10,16,18-19,21,32H,8-9,11-14H2,1-7H3,(H,36,37)/b15-10-/t16?,18-,19+,21+,28+,29-,30+/m1/s1
SMILES Code
C/C([C@H]([C@@]1(C)C2)CC([C@@]1(C)C([C@@H](O)C[C@@]3([H])C(C)(C)C(CC[C@]43C)=O)=C4C2=O)=O)=C/C(CC(C)C(O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 512.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Che XQ, Li SP, Zhao J. [Ganoderma triterpenoids from aqueous extract of Ganoderma lucidum]. Zhongguo Zhong Yao Za Zhi. 2017 May;42(10):1908-1915. doi: 10.19540/j.cnki.cjcmm.20170412.001. Chinese. PubMed PMID: 29090550. 2: Zhao RL, He YM. Network pharmacology analysis of the anti-cancer pharmacological mechanisms of Ganoderma lucidum extract with experimental support using Hepa1-6-bearing C57 BL/6 mice. J Ethnopharmacol. 2018 Jan 10;210:287-295. doi: 10.1016/j.jep.2017.08.041. Epub 2017 Sep 4. PubMed PMID: 28882624. 3: Liu LY, Kang J, Wu CH, Li Y, Chen RY. [Triterpenoids from Ganoderma theaecolum]. Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(6):1075-1080. doi: 10.4268/cjcmm20160617. Chinese. PubMed PMID: 28875673. 4: Ruan W, Lim AH, Huang LG, Popovich DG. Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growth. Nat Prod Res. 2014;28(24):2264-72. doi: 10.1080/14786419.2014.938337. Epub 2014 Jul 17. PubMed PMID: 25032738. 5: Li BM, Gu HF, Li Y, Liu C, Wang HQ, Kang J, Wu CH, Chen RY. [Determination of nine triterpenoid acids from Ganoderma lucidum of different producting areas by HPLC]. Zhongguo Zhong Yao Za Zhi. 2012 Dec;37(23):3599-603. Chinese. PubMed PMID: 23477148. 6: Zhao J, Chen X, Bi K. [Simultaneous HPLC determination of four triterpenoid acids in Ganoderma lucidum]. Zhongguo Zhong Yao Za Zhi. 2009 Sep;34(17):2220-2. Chinese. PubMed PMID: 19943490. 7: Wang F, Liu JK. Highly oxygenated lanostane triterpenoids from the fungus Ganoderma applanatum. Chem Pharm Bull (Tokyo). 2008 Jul;56(7):1035-7. PubMed PMID: 18591828. 8: Rösecke J, König WA. Constituents of various wood-rotting basidiomycetes. Phytochemistry. 2000 Jul;54(6):603-10. PubMed PMID: 10963454.