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MedKoo Cat#: 561724 | Name: Sodium Oxamate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sodium Oxamate is an LDH inhibitor. It inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway.

Chemical Structure

Sodium Oxamate
Sodium Oxamate
CAS#565-73-1

Theoretical Analysis

MedKoo Cat#: 561724

Name: Sodium Oxamate

CAS#: 565-73-1

Chemical Formula: C2H2NNaO3

Exact Mass:

Molecular Weight: 111.03

Elemental Analysis: C, 21.64; H, 1.82; N, 12.62; Na, 20.71; O, 43.23

Price and Availability

Size Price Availability Quantity
5g USD 200.00
10g USD 340.00
25g USD 630.00
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Related CAS #
No Data
Synonym
Sodium Oxamate;
IUPAC/Chemical Name
Aminooxoacetic acid sodium salt
InChi Key
RQVZIJIQDCGIKI-UHFFFAOYSA-M
InChi Code
InChI=1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
SMILES Code
O=C([O-])C(N)=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 111.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 21325689. 9: Kostesha N, Willquist K, Emneus J, van Niel EW. Probing the redox metabolism in the strictly anaerobic, extremely thermophilic, hydrogen-producing Caldicellulosiruptor saccharolyticus using amperometry. Extremophiles. 2011 Jan;15(1):77-87. doi: 10.1007/s00792-010-0341-4. Epub 2010 Dec 4. PubMed PMID: 21132340. 10: O'Flaherty C, Breininger E, Beorlegui N, Beconi MT. Acrosome reaction in bovine spermatozoa: role of reactive oxygen species and lactate dehydrogenase C4. Biochim Biophys Acta. 2005 Oct 30;1726(1):96-101. Epub 2005 Aug 8. PubMed PMID: 16112812. 11: O'Flaherty CM, Beorlegui NB, Beconi MT. Lactate dehydrogenase-C4 is involved in heparin- and NADH-dependent bovine sperm capacitation. Andrologia. 2002 Apr;34(2):91-7. Erratum in: Andrologia. 2002 Dec;34(6):405.. PubMed PMID: 11966575. 12: Aitken RJ, Fisher HM, Fulton N, Gomez E, Knox W, Lewis B, Irvine S. Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine. Mol Reprod Dev. 1997 Aug;47(4):468-82. PubMed PMID: 9211432. 13: Hillman JD, Duncan MJ, Stashenko KP. Cloning and expression of the gene encoding the fructose-1,6-diphosphate-dependent L-(+)-lactate dehydrogenase of Streptococcus mutans. Infect Immun. 1990 May;58(5):1290-5. PubMed PMID: 2323817; PubMed Central PMCID: PMC258622. 14: Wigley DB, Muirhead H, Gamblin SJ, Holbrook JJ. Crystallization of a ternary complex of lactate dehydrogenase from Bacillus stearothermophilus. J Mol Biol. 1988 Dec 20;204(4):1041-3. PubMed PMID: 3065514. 15: Rohde MD, Huff JW. Contact lens-induced edema in vitro--amelioration by lactate dehydrogenase inhibitors. Curr Eye Res. 1986 Oct;5(10):751-8. PubMed PMID: 3769523. 16: Hood RL, Beitz DC, Johnson DC. Inhibition by potential metabolic inhibitors of in vitro adipose tissue lipogenesis. 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