MedKoo Cat#: 597143 | Name: Sodium lauroyl glutamate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sodium lauroyl glutamate is derived from glutamic acid (an amino acid), lauric acid (a fatty acid derived from renewable plant resources) and sodium. It is used as a gentle cleanser more suitable for sensitive skin.

Chemical Structure

Sodium lauroyl glutamate
Sodium lauroyl glutamate
CAS#29923-31-7

Theoretical Analysis

MedKoo Cat#: 597143

Name: Sodium lauroyl glutamate

CAS#: 29923-31-7

Chemical Formula: C17H30NNaO5

Exact Mass:

Molecular Weight: 351.41

Elemental Analysis: C, 58.10; H, 8.61; N, 3.99; Na, 6.54; O, 22.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Sodium lauroyl glutamate; Hostapon CLG; Amisoft LS 11; Acylglutamate LS-11; Sodium N-lauroylglutamate;
IUPAC/Chemical Name
sodium (S)-4-carboxy-2-dodecanamidobutanoate
InChi Key
IWIUXJGIDSGWDN-UQKRIMTDSA-M
InChi Code
InChI=1S/C17H31NO5.Na/c1-2-3-4-5-6-7-8-9-10-11-15(19)18-14(17(22)23)12-13-16(20)21;/h14H,2-13H2,1H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/t14-;/m0./s1
SMILES Code
O=C(O)CC[C@@H](C([O-])=O)NC(CCCCCCCCCCC)=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 351.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Burnett CL, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. Int J Toxicol. 2017 May/Jun;36(1_suppl):17S-56S. doi: 10.1177/1091581816686048. PubMed PMID: 28553738. 2: Ariki R, Hirano A, Arakawa T, Shiraki K. Drug solubilization effect of lauroyl-L-glutamate. J Biochem. 2012 Jan;151(1):27-33. doi: 10.1093/jb/mvr117. Epub 2011 Sep 23. PubMed PMID: 21949409. 3: Corazza M, Lauriola MM, Bianchi A, Zappaterra M, Virgili A. Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients. Dermatitis. 2010 Sep-Oct;21(5):262-8. PubMed PMID: 20920412. 4: Chen Z, Liu J, Han Y. Rapid and sensitive determination of proteins by enhanced resonance light scattering spectroscopy of sodium lauroyl glutamate. Talanta. 2007 Feb 28;71(3):1246-51. doi: 10.1016/j.talanta.2006.06.025. Epub 2006 Jul 27. PubMed PMID: 19071440. 5: Rosa M, Rosa Infante M, Miguel Mda G, Lindman B. Spontaneous formation of vesicles and dispersed cubic and hexagonal particles in amino acid-based catanionic surfactant systems. Langmuir. 2006 Jun 20;22(13):5588-96. PubMed PMID: 16768481. 6: Kawasaki Y, Quan D, Sakamoto K, Maibach HI. Electron resonance studies on the influence of anionic surfactants on human skin. Dermatology. 1997;194(3):238-42. PubMed PMID: 9187840. 7: Lee CH, Kawasaki Y, Maibach HI. Effect of surfactant mixtures on irritant contact dermatitis potential in man: sodium lauroyl glutamate and sodium lauryl sulphate. Contact Dermatitis. 1994 Apr;30(4):205-9. PubMed PMID: 8033544.