MedKoo Cat#: 561675 | Name: iKIX1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

iKIX1 is an inhibitor of Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection.

Chemical Structure

iKIX1
iKIX1
CAS#656222-54-7

Theoretical Analysis

MedKoo Cat#: 561675

Name: iKIX1

CAS#: 656222-54-7

Chemical Formula: C10H8Cl2N4OS

Exact Mass: 301.9796

Molecular Weight: 303.16

Elemental Analysis: C, 39.62; H, 2.66; Cl, 23.39; N, 18.48; O, 5.28; S, 10.58

Price and Availability

Size Price Availability Quantity
5mg USD 150.00 2 Weeks
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
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Related CAS #
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Synonym
iKIX1; iKIX-1; iKIX 1;
IUPAC/Chemical Name
2-Cyano-acetic acid 2-[[(3,4-dichlorophenyl)amino]thioxomethyl]hydrazide
InChi Key
XKQJVBSDCOCZFV-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H8Cl2N4OS/c11-7-2-1-6(5-8(7)12)14-10(18)16-15-9(17)3-4-13/h1-2,5H,3H2,(H,15,17)(H2,14,16,18)
SMILES Code
O=C(NNC(NC1=CC=C(Cl)C(Cl)=C1)=S)CC#N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 303.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H. Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction. Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17. PubMed PMID: 26886795; PubMed Central PMCID: PMC4860947.