MedKoo Cat#: 561657 | Name: XMD-17-51
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

XMD-17-51 is a potent and selective NUAK1 inhibitor.

Chemical Structure

XMD-17-51
XMD-17-51
CAS#1628614-50-5 (free base)

Theoretical Analysis

MedKoo Cat#: 561657

Name: XMD-17-51

CAS#: 1628614-50-5 (free base)

Chemical Formula: C21H24N8O

Exact Mass: 404.2073

Molecular Weight: 404.47

Elemental Analysis: C, 62.36; H, 5.98; N, 27.70; O, 3.96

Price and Availability

Size Price Availability Quantity
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
1628614-50-5 (free base) 2436579-93-8 (TFA)
Synonym
XMD-17-51; XMD 17 51; XMD1751;
IUPAC/Chemical Name
5,11-Dihydro-5,11-dimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
InChi Key
LKOFXMLMYKWELM-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H24N8O/c1-27-17-6-4-3-5-16(17)20(30)28(2)18-12-23-21(26-19(18)27)25-14-11-24-29(13-14)15-7-9-22-10-8-15/h3-6,11-13,15,22H,7-10H2,1-2H3,(H,23,25,26)
SMILES Code
O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 404.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Yang WQ, Zhao WJ, Zhu LL, Xu SJ, Zhang XL, Liang Y, Ding XF, Kiselyov A, Chen G. XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression. Front Pharmacol. 2021 Mar 8;12:603453. doi: 10.3389/fphar.2021.603453. PMID: 33762936; PMCID: PMC7982674.