KYA1797 is a novel inhibitor of the Wnt/ß-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppressing the growth of CRCs harboring APC and KRAS mutations.
MedKoo Cat#: 526491
Name: KYA1797
CAS#: 851304-36-4
Chemical Formula: C17H12N2O6S2
Exact Mass: 404.0100
Molecular Weight: 404.41
Elemental Analysis: C, 50.49; H, 2.99; N, 6.93; O, 23.74; S, 15.86
The following data is based on the product molecular weight 404.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
