MedKoo Cat#: 526486 | Name: SNAP-5089
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SNAP-5089 (SNAP 5089) is a highly selective α1A-adrenoceptor antagonist. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

SNAP-5089
SNAP-5089
CAS#157066-77-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 526486

Name: SNAP-5089

CAS#: 157066-77-8 (HCl)

Chemical Formula: C36H41ClN4O5

Exact Mass: 644.2800

Molecular Weight: 645.20

Elemental Analysis: C, 67.02; H, 6.41; Cl, 5.49; N, 8.68; O, 12.40

Price and Availability

Size Price Availability Quantity
10mg USD 500.00 2 Weeks
50mg USD 1,000.00 2 Weeks
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Related CAS #
157066-76-7 (free base) 157066-77-8 (HCl)
Synonym
SNAP-5089; SNAP 5089; SNAP5089;
IUPAC/Chemical Name
5-[[[3-(4,4-Diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3-pyridinecarboxylic acid methyl ester hydrochloride
InChi Key
MXELDPKESKXREN-UHFFFAOYSA-N
InChi Code
InChI=1S/C36H40N4O5.ClH/c1-25-31(33(32(26(2)38-25)35(42)45-3)27-15-17-30(18-16-27)40(43)44)34(41)37-21-10-22-39-23-19-36(20-24-39,28-11-6-4-7-12-28)29-13-8-5-9-14-29;/h4-9,11-18,33,38H,10,19-24H2,1-3H3,(H,37,41);1H
SMILES Code
O=C(C1=C(C)NC(C)=C(C(NCCCN2CCC(C3=CC=CC=C3)(C4=CC=CC=C4)CC2)=O)C1C5=CC=C([N+]([O-])=O)C=C5)OC.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 645.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kava MS, Blue DR Jr, Vimont RL, Clarke DE, Ford AP. Alpha1L-adrenoceptor mediation of smooth muscle contraction in rabbit bladder neck: a model for lower urinary tract tissues of man. Br J Pharmacol. 1998 Apr;123(7):1359-66. PubMed PMID: 9579731; PubMed Central PMCID: PMC1565303. 2: Lachnit WG, Tran AM, Clarke DE, Ford AP. Pharmacological characterization of an alpha 1A-adrenoceptor mediating contractile responses to noradrenaline in isolated caudal artery of rat. Br J Pharmacol. 1997 Mar;120(5):819-26. PubMed PMID: 9138687; PubMed Central PMCID: PMC1564543.