NNC-38-1049 | CAS#757183-18-9

MedKoo Cat#: 526463 | Name: NNC-38-1049

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NNC-38-1049 is a novel selective histamine H3 antagonist.

Chemical Structure

NNC-38-1049

CAS#757183-18-9

Theoretical Analysis

MedKoo Cat#: 526463

Name: NNC-38-1049

CAS#: 757183-18-9

Chemical Formula: C19H25ClN2O2

Exact Mass: 348.1600

Molecular Weight: 348.87

Elemental Analysis: C, 65.41; H, 7.22; Cl, 10.16; N, 8.03; O, 9.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NNC-38-1049; NNC 38-1049; NNC38-1049; NNC-381049; NNC 381049; NNC381049;

IUPAC/Chemical Name

1-(4-Chlorophenyl)-4-(4-cyclopentylpiperazine-1-yl)-4-oxobutan-1-one

InChi Key

VPARRMQGLNFBBR-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H25ClN2O2/c20-16-7-5-15(6-8-16)18(23)9-10-19(24)22-13-11-21(12-14-22)17-3-1-2-4-17/h5-8,17H,1-4,9-14H2

SMILES Code

O=C(C1=CC=C(Cl)C=C1)CCC(N2CCN(C3CCCC3)CC2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 348.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Malmlöf K, Golozoubova V, Peschke B, Wulff BS, Refsgaard HH, Johansen PB, Cremers T, Rimvall K. Increase of neuronal histamine in obese rats is associated with decreases in body weight and plasma triglycerides. Obesity (Silver Spring). 2006 Dec;14(12):2154-62. PubMed PMID: 17189541. 2: Malmlöf K, Zaragoza F, Golozoubova V, Refsgaard HH, Cremers T, Raun K, Wulff BS, Johansen PB, Westerink B, Rimvall K. Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight. Int J Obes (Lond). 2005 Dec;29(12):1402-12. PubMed PMID: 16151415.