Benalaxyl | CAS#71626-11-4 | Fungicide

MedKoo Cat#: 584145 | Name: Benalaxyl

Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Benalaxyl is an agricultural chemical typically used as a fungicide.

Chemical Structure

Benalaxyl

CAS#71626-11-4

Theoretical Analysis

MedKoo Cat#: 584145

Name: Benalaxyl

CAS#: 71626-11-4

Chemical Formula: C20H23NO3

Exact Mass: 325.1678

Molecular Weight: 325.40

Elemental Analysis: C, 73.82; H, 7.12; N, 4.30; O, 14.75

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 450.00	Back order

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

71626-11-4 97716-85-3 (S isomer)

Synonym

Benalaxyl; Galben; M 9834; M-9834; M9834; BRN 3001587; BRN-3001587; BRN3001587

IUPAC/Chemical Name

methyl N-(2,6-dimethylphenyl)-N-(2-phenylacetyl)alaninate

InChi Key

CJPQIRJHIZUAQP-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3

SMILES Code

COC(C(N(C1=C(C)C=CC=C1C)C(CC2=CC=CC=C2)=O)C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 325.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wang X, Wang D, Zhou Z, Zhu W. Subacute oral toxicity assessment of benalaxyl in mice based on metabolomics methods. Chemosphere. 2018 Jan;191:373-380. doi: 10.1016/j.chemosphere.2017.10.085. Epub 2017 Oct 15. PubMed PMID: 29054078. 2: Jing X, Yao G, Liu D, Liang Y, Luo M, Zhou Z, Wang P. Effects of wastewater irrigation and sewage sludge application on soil residues of chiral fungicide benalaxyl. Environ Pollut. 2017 May;224:1-6. doi: 10.1016/j.envpol.2017.03.004. Epub 2017 Mar 10. PubMed PMID: 28288350. 3: Wang X, Zhu W, Qiu J, Wang D, Zhou Z. Enantioselective metabolism and enantiomerization of benalaxyl in mice. Chemosphere. 2017 Feb;169:308-315. doi: 10.1016/j.chemosphere.2016.11.091. Epub 2016 Nov 22. PubMed PMID: 27886532. 4: Lu Y, Shao Y, Dai S, Diao J, Chen X. Stereoselective Behavior of the Fungicide Benalaxyl During Grape Growth and the Wine-Making Process. Chirality. 2016 May;28(5):394-8. doi: 10.1002/chir.22589. Epub 2016 Mar 2. PubMed PMID: 26934695. 5: Wang X, Wang D, Wang Y, Zhang P, Zhou Z, Zhu W. A combined non-targeted and targeted metabolomics approach to study the stereoselective metabolism of benalaxyl enantiomers in mouse hepatic microsomes. Environ Pollut. 2016 May;212:358-365. doi: 10.1016/j.envpol.2016.01.081. Epub 2016 Feb 10. PubMed PMID: 26874317. 6: Liu M, Liu D, Xu Y, Jing X, Zhou Z, Wang P. Fate and stereoselective behavior of benalaxyl in a water-sediment microcosm. J Agric Food Chem. 2015 Jun 3;63(21):5205-11. doi: 10.1021/acs.jafc.5b01448. Epub 2015 May 26. PubMed PMID: 26009811. 7: Qin F, Gao YX, Guo BY, Xu P, Li JZ, Wang HL. Environmental behavior of benalaxyl and furalaxyl enantiomers in agricultural soils. J Environ Sci Health B. 2014;49(10):738-46. doi: 10.1080/03601234.2014.929482. PubMed PMID: 25065825. 8: Wang Y, Guo B, Gao Y, Xu P, Zhang Y, Li J, Wang H. Stereoselective degradation and toxic effects of benalaxyl on blood and liver of the Chinese lizard Eremias argus. Pestic Biochem Physiol. 2014 Jan;108:34-41. doi: 10.1016/j.pestbp.2013.11.004. Epub 2013 Dec 4. PubMed PMID: 24485313. 9: Gao Y, Chen J, Wang H, Liu C, Lv X, Li J, Guo B. Enantiomerization and enantioselective bioaccumulation of benalaxyl in Tenebrio molitor larvae from wheat bran. J Agric Food Chem. 2013 Sep 25;61(38):9045-51. doi: 10.1021/jf4020125. Epub 2013 Sep 13. PubMed PMID: 24000806. 10: Nallani GC, ElNaggar SF, Shen L, Chandrasekaran A. In vitro metabolism of [(14)C]-benalaxyl in hepatocytes of rats, dogs and humans. Regul Toxicol Pharmacol. 2017 Mar;84:26-34. doi: 10.1016/j.yrtph.2016.12.006. Epub 2016 Dec 18. PubMed PMID: 27993653. 11: Gu X, Yao T. The integration of in vivo and in vitro metabolism assays to investigate the stereoselective behaviors of benalaxyl in rainbow trout (Oncorhynchus mykiss). J Environ Sci Health B. 2013;48(8):693-9. doi: 10.1080/03601234.2013.778631. Erratum in: J Environ Sci Health B. 2013;48(12):1121. PubMed PMID: 23638897. 12: Kundu C, Goon A, Bhattacharyya A. Persistence behaviour of fungicide mixture (benalaxyl-M 4% + mancozeb 65%) WP in grapes. Bull Environ Contam Toxicol. 2012 Dec;89(6):1253-7. doi: 10.1007/s00128-012-0847-9. Epub 2012 Oct 2. PubMed PMID: 23052585. 13: Huang L, Lu D, Diao J, Zhou Z. Enantioselective toxic effects and biodegradation of benalaxyl in Scenedesmus obliquus. Chemosphere. 2012 Mar;87(1):7-11. doi: 10.1016/j.chemosphere.2011.11.029. Epub 2011 Dec 9. PubMed PMID: 22169712. 14: Pérez-Fernández V, García MÁ, Marina ML. Chiral separation of metalaxyl and benalaxyl fungicides by electrokinetic chromatography and determination of enantiomeric impurities. J Chromatogr A. 2011 Jul 29;1218(30):4877-85. doi: 10.1016/j.chroma.2010.12.116. Epub 2011 Jan 5. PubMed PMID: 21272886. 15: Zhang P, Zhu W, Dang Z, Shen Z, Xu X, Huang L, Zhou Z. Stereoselective metabolism of benalaxyl in liver microsomes from rat and rabbit. Chirality. 2011 Feb;23(2):93-8. doi: 10.1002/chir.20879. PubMed PMID: 20544700. 16: Xu P, Liu D, Diao J, Lu D, Zhou Z. Enantioselective acute toxicity and bioaccumulation of benalaxyl in earthworm (Eisenia fedtia). J Agric Food Chem. 2009 Sep 23;57(18):8545-9. doi: 10.1021/jf902420a. PubMed PMID: 19694444. 17: Gu X, Wang P, Liu D, Lv C, Lu Y, Zhou Z. Stereoselective degradation of benalaxyl in tomato, tobacco, sugar beet, capsicum, and soil. Chirality. 2008 Feb;20(2):125-9. PubMed PMID: 18092301. 18: Wang X, Jia G, Qiu J, Diao J, Zhu W, Lv C, Zhou Z. Stereoselective degradation of fungicide benalaxyl in soils and cucumber plants. Chirality. 2007 May 5;19(4):300-6. PubMed PMID: 17345561. 19: Qiu J, Wang Q, Zhu W, Jia G, Wang X, Zhou Z. Stereoselective determination of benalaxyl in plasma by chiral high-performance liquid chromatography with diode array detector and application to pharmacokinetic study in rabbits. Chirality. 2007 Jan;19(1):51-5. PubMed PMID: 17089341. 20: Patakioutas GI, Karras G, Hela D, Albanis TA. Pirimiphos-methyl and benalaxyl losses in surface runoff from plots cultivated with potatoes. Pest Manag Sci. 2002 Dec;58(12):1194-204. PubMed PMID: 12476992.