Synonym
Ioglycamic acid; Ioglycamide; BE 419; BE-419; BE419
IUPAC/Chemical Name
Benzoic acid, 3,3'-(oxybis((1-oxo-2,1-ethanediyl)imino))bis(2,4,6-triiodo-
InChi Key
FZDZULUFHNDEDJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H10I6N2O7/c19-5-1-7(21)15(13(23)11(5)17(29)30)25-9(27)3-33-4-10(28)26-16-8(22)2-6(20)12(14(16)24)18(31)32/h1-2H,3-4H2,(H,25,27)(H,26,28)(H,29,30)(H,31,32)
SMILES Code
O=C(NC1=C(I)C(C(O)=O)=C(I)C=C1I)COCC(NC2=C(I)C(C(O)=O)=C(I)C=C2I)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
1,127.71
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Fleck C, Kabath P, Linstedt A, Linstedt U, Scharke U, Bräunlich H. Relation between renal and hepatic excretion of drugs. XIV. Elimination of ioglycamic acid after nephrectomy, bile duct ligation, and after treatment with hormones or xenobiotics in young and adult rats. Exp Pathol. 1991;43(1-2):75-87. PubMed PMID: 1783049.
2: Blackwell JN, Finlayson ND, McLoughlin GP, Sumerling MD, Tothill P. Iodine 131 labelled ioglycamic acid (Biligram) for scintiscanning in hepatobiliary disorders. Eur J Nucl Med. 1979 Feb 1;4(1):7-11. PubMed PMID: 499229.
3: Strecker EP, Kraemer C, Reinbold WD, Speck U. Inhalation bronchography using powdered calcium ioglycamic acid. Radiology. 1979 Feb;130(2):303-9. PubMed PMID: 104359.
4: Mützel W, Taenzer V, Wolf R. Biotransformation of ioglycamic acid, iodoxamic acid and iotroxic acid in man. Invest Radiol. 1976 Nov-Dec;11(6):598-601. PubMed PMID: 1036733.
