MedKoo Cat#: 561598 | Name: Adrenalone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic.

Chemical Structure

Adrenalone
CAS#99-45-6 (free base)

Theoretical Analysis

MedKoo Cat#: 561598

Name: Adrenalone

CAS#: 99-45-6 (free base)

Chemical Formula: C9H11NO3

Exact Mass: 181.0700

Molecular Weight: 181.19

Elemental Analysis: C, 59.66; H, 6.12; N, 7.73; O, 26.49

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 Back order
100mg USD 650.00 Back order
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Synonym
Adrenalone; Adrenone; Chemosan; Haemodan; Kephrine; Ketogaze, Methaminoacetocatechol, Remestyp, Stryphnon, U 2134
IUPAC/Chemical Name
1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone
InChi Key
PZMVOUYYNKPMSI-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H11NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,10-12H,5H2,1H3
SMILES Code
CNCC(C1=CC=C(O)C(O)=C1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 181.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kulinskiĭ VI, Iashunskiĭ VG, Klimova AD, Alpatova TV. [Radiation protective effect of beta-ketoanalogs of hydroxyphenyl ethanolamines]. Radiats Biol Radioecol. 1997 Nov-Dec;37(6):914-7. Russian. PubMed PMID: 9467647. 2: Lernhardt U, Strobel G, Schell H, Werle E, Weicker H. Modified syntheses of dopamine-4-sulfate, epinephrine-3-sulfate, and norepinephrine-3-sulfate: determination of the position of the sulfate group by 1H-NMR spectroscopy. Int J Sports Med. 1988 Aug;9 Suppl 2:S89-92. PubMed PMID: 3182167. 3: Kirchhoefer RD, Sullivan GM, Allgire JF. Analysis of USP epinephrine injections for potency, impurities, degradation products, and d-enantiomer by liquid chromatography, using ultraviolet and electrochemical detectors. J Assoc Off Anal Chem. 1985 Mar-Apr;68(2):163-5. PubMed PMID: 3988695. 4: Bodor N, Visor G. Improved Delivery Through Biological Membranes. XVII. A Site-Specific Chemical Delivery System as a Short-Acting Mydriatic Agent. Pharm Res. 1984 Jul;1(4):168-73. doi: 10.1023/A:1016348624897. PubMed PMID: 24277286. 5: Bodor N, Visor G. Formation of adrenaline in the iris-ciliary body from adrenalone diesters. Exp Eye Res. 1984 Jun;38(6):621-6. PubMed PMID: 6547911. 6: Kalyanaraman B, Felix CC, Sealy RC. Electron spin resonance-spin stabilization of semiquinones produced during oxidation of epinephrine and its analogues. J Biol Chem. 1984 Jan 10;259(1):354-8. PubMed PMID: 6323406. 7: Hazard R, Mouillé P. [Relations between the amine and alcohol functions of adrenaline and its hyperglycemic action. Comparative actions in the rabbit (intravenous route) of noradrenaline, ethylnoradrenaline and isoprenaline; of adrenalone, hydroxytyramine and epinine]. J Physiol (Paris). 1965 May-Jun;57(3):399-406. French. PubMed PMID: 5838236. 8: GOLDSTEIN M, MUSACCHIO JM, KENIN MC, CONTRERA JF, RICE MD. The inhibition in vivo of norepinephrine synthesis by adrenalone. Biochem Pharmacol. 1962 Aug;11:809-11. PubMed PMID: 13899911. 9: GOLDSTEIN M, CONTRERA JF. Inhibition of dopamine beta oxidase by adrenalone. Nature. 1961 Dec 16;192:1081. PubMed PMID: 13899905. 10: WEIDNER G, WEISS F. [Detection of adrenalone by means of paper chromatography even in the presence of other phenylethylamine derivatives]. Pharmazie. 1958 Jul;13(7):395-402. German. PubMed PMID: 13578644. 11: WEIDNER G. [Quantitative determination of adrenalone, especially in the presence of adrenalin]. Hoppe Seylers Z Physiol Chem. 1958;312(4-6):202-5. German. PubMed PMID: 13620204. 12: VOGELER L, REICHARDT A. [The effects of yohimbine and theophylline on subliminal doses of adrenalone]. Dtsch Med J. 1954 Oct 15;5(19-20):590-2. German. PubMed PMID: 13220295. 13: REICHELT J. [Electrophotometric determination of adrenalone]. Cesk Farm. 1953 Sep;2(9):291-3. Undetermined Language. PubMed PMID: 13116243. 14: OSINSKAIA VO. [Data on oxidation of adrenalin, noradrenalin, adrenalone and noradrenalone into fluorescent compound]. Biokhimiia. 1953 Jan-Feb;18(1):56-62. Undetermined Language. PubMed PMID: 13140375. 15: RAVINA A, MAIGNAN P. [Adrenalone: chemical and pharmacological properties; application in the treatment of asthma and asthmatiform dyspneas]. Therapie. 1953;8(3):224-30. Undetermined Language. PubMed PMID: 13136023. 16: LUDWIGS N, SCHNEIDER M. [Broncholytic effect of aralkyl adrenalin and adrenalone derivatives]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;218(6):432-42. Undetermined Language. PubMed PMID: 13119756. 17: VISINTIN B. [Adrenalin from adrenalone by catalytic reduction with Raney's nickel]. Rend Ist Sup Sanit. 1951;14(9):686-91. Undetermined Language. PubMed PMID: 14900491.